• Target：
• CD48

• Fields：
• >>Natural killer cell mediated cytotoxicity

• Gene Name：
• CD48

• Protein Name：
• CD48 antigen

• Human Gene Id：
• 962

• Human Swiss Prot No：
• P09326

• Mouse Swiss Prot No：
• P18181

• Immunogen：
• The antiserum was produced against synthesized peptide derived from the Internal region of human CD48. AA range:41-90

• Specificity：
• CD48 Polyclonal Antibody detects endogenous levels of CD48 protein.

• Formulation：
• Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

• Source：
• Polyclonal, Rabbit,IgG

• Dilution：
• WB 1:500 - 1:2000. IHC: 1:100-300 ELISA: 1:20000.. IF 1:50-200

• Purification：
• The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

• Concentration：
• 1 mg/ml

• Storage Stability：
• -15°C to -25°C/1 year(Do not lower than -25°C)

• Other Name：
• CD48;BCM1;BLAST1;CD48 antigen;B-lymphocyte activation marker BLAST-1;BCM1 surface antigen;Leukocyte antigen MEM-102;TCT.1;CD48

• Observed Band(KD)：
• 40kD

• Background：
• This gene encodes a member of the CD2 subfamily of immunoglobulin-like receptors which includes SLAM (signaling lymphocyte activation molecules) proteins. The encoded protein is found on the surface of lymphocytes and other immune cells, dendritic cells and endothelial cells, and participates in activation and differentiation pathways in these cells. The encoded protein does not have a transmembrane domain, however, but is held at the cell surface by a GPI anchor via a C-terminal domain which maybe cleaved to yield a soluble form of the receptor. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Dec 2011],

• Function：
• function:Ligand for CD2. Might facilitate interaction between activated lymphocytes. Probably involved in regulating T-cell activation.,similarity:Contains 1 Ig-like C2-type (immunoglobulin-like) domain.,similarity:Contains 1 Ig-like V-type (immunoglobulin-like) domain.,

• Subcellular Location：
• Cell membrane ; Lipid-anchor, GPI-anchor . Secreted .

• Expression：
• Widely expressed on all hematopoietic cells.

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