DNA Pol μ Polyclonal Antibody

    • Catalog No.:YT5105
    • Applications:WB;ELISA
    • Reactivity:Human;Rat;Mouse;
      • Target:
      • DNA Pol μ
      • Fields:
      • >>Non-homologous end-joining
      • Gene Name:
      • POLM
      • Protein Name:
      • DNA-directed DNA/RNA polymerase mu
      • Human Swiss Prot No:
      • Q9NP87
      • Mouse Swiss Prot No:
      • Q9JIW4
      • Immunogen:
      • Synthesized peptide derived from DNA Pol μ . at AA range: 210-290
      • Specificity:
      • DNA Pol μ Polyclonal Antibody detects endogenous levels of DNA Pol μ protein.
      • Formulation:
      • Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
      • Source:
      • Polyclonal, Rabbit,IgG
      • Dilution:
      • WB 1:500 - 1:2000. ELISA: 1:40000. Not yet tested in other applications.
      • Purification:
      • The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
      • Concentration:
      • 1 mg/ml
      • Storage Stability:
      • -15°C to -25°C/1 year(Do not lower than -25°C)
      • Other Name:
      • POLM;polmu;DNA-directed DNA/RNA polymerase mu;Pol Mu;Terminal transferase
      • Observed Band(KD):
      • 54kD
      • Background:
      • catalytic activity:Deoxynucleoside triphosphate + DNA(n) = diphosphate + DNA(n+1).,cofactor:Magnesium.,function:Seems to act as an Ig mutase which is responsible for immunoglobulin (Ig) gene hypermutation.,similarity:Belongs to the DNA polymerase type-X family.,similarity:Contains 1 BRCT domain.,tissue specificity:Expressed in a number of tissues. Abundant in thymus.,
      • Function:
      • catalytic activity:Deoxynucleoside triphosphate + DNA(n) = diphosphate + DNA(n+1).,cofactor:Magnesium.,function:Seems to act as an Ig mutase which is responsible for immunoglobulin (Ig) gene hypermutation.,similarity:Belongs to the DNA polymerase type-X family.,similarity:Contains 1 BRCT domain.,tissue specificity:Expressed in a number of tissues. Abundant in thymus.,
      • Subcellular Location:
      • Nucleus .
      • Expression:
      • Expressed in a number of tissues. Abundant in thymus.
      • Products Images
      • Western Blot analysis of extracts from K562 cells, using DNA Pol μ Polyclonal Antibody. Secondary antibody(catalog#:RS0002) was diluted at 1:20000 cells nucleus extracted by Minute TM Cytoplasmic and Nuclear Fractionation kit (SC-003,Inventbiotech,MN,USA).