PDP2 Polyclonal Antibody

    • Catalog No.:YT5074
    • Applications:WB;ELISA;IHC
    • Reactivity:Human;Rat;Mouse;
      • Target:
      • PDP2
      • Gene Name:
      • PDP2
      • Protein Name:
      • [Pyruvate dehydrogenase [acetyl-transferring]]-phosphatase 2 mitochondrial
      • Human Swiss Prot No:
      • Q9P2J9
      • Immunogen:
      • Synthesized peptide derived from PDP2 . at AA range: 70-150
      • Specificity:
      • PDP2 Polyclonal Antibody detects endogenous levels of PDP2 protein.
      • Formulation:
      • Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
      • Source:
      • Polyclonal, Rabbit,IgG
      • Dilution:
      • WB 1:500-2000;IHC 1:50-300; ELISA 2000-20000
      • Purification:
      • The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
      • Concentration:
      • 1 mg/ml
      • Storage Stability:
      • -15°C to -25°C/1 year(Do not lower than -25°C)
      • Other Name:
      • PDP2;KIAA1348;[Pyruvate dehydrogenase [acetyl-transferring]]-phosphatase 2, mitochondrial;PDP 2;Pyruvate dehydrogenase phosphatase catalytic subunit 2;PDPC 2
      • Observed Band(KD):
      • 59kD
      • Background:
      • This gene is a mitochondrial protein that functions as a phosphatase and is involved in the enzymatic resetting of the pyruvate dehydrogenase complex. Alternative splicing results in multiple transcript variants encoding the same protein. [provided by RefSeq, Aug 2016],
      • Function:
      • catalytic activity:[Pyruvate dehydrogenase (acetyl-transferring)] phosphate + H(2)O = [pyruvate dehydrogenase (acetyl-transferring)] + phosphate.,cofactor:Binds 2 magnesium ions per subunit.,function:Catalyzes the dephosphorylation and concomitant reactivation of the alpha subunit of the E1 component of the pyruvate dehydrogenase complex.,similarity:Belongs to the PP2C family.,subunit:Heterodimer of a catalytic subunit and a FAD protein of unknown function.,
      • Subcellular Location:
      • Mitochondrion matrix .
      • Expression:
      • Brain,
      • Products Images
      • Western Blot analysis of extracts from K562 cells, using PDP2 Polyclonal Antibody. Secondary antibody(catalog#:RS0002) was diluted at 1:20000
      • Immunohistochemical analysis of paraffin-embedded human Gastric adenocarcinoma. 1, Antibody was diluted at 1:200(4° overnight). 2, Tris-EDTA,pH9.0 was used for antigen retrieval. 3,Secondary antibody was diluted at 1:200(room temperature, 45min).