PDP2 Polyclonal Antibody
- Catalog No.:YT5074
- Applications:WB;ELISA;IHC
- Reactivity:Human;Rat;Mouse;
- Target:
- PDP2
- Gene Name:
- PDP2
- Protein Name:
- [Pyruvate dehydrogenase [acetyl-transferring]]-phosphatase 2 mitochondrial
- Human Gene Id:
- 57546
- Human Swiss Prot No:
- Q9P2J9
- Immunogen:
- Synthesized peptide derived from PDP2 . at AA range: 70-150
- Specificity:
- PDP2 Polyclonal Antibody detects endogenous levels of PDP2 protein.
- Formulation:
- Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
- Source:
- Polyclonal, Rabbit,IgG
- Dilution:
- WB 1:500-2000;IHC 1:50-300; ELISA 2000-20000
- Purification:
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
- Concentration:
- 1 mg/ml
- Storage Stability:
- -15°C to -25°C/1 year(Do not lower than -25°C)
- Other Name:
- PDP2;KIAA1348;[Pyruvate dehydrogenase [acetyl-transferring]]-phosphatase 2, mitochondrial;PDP 2;Pyruvate dehydrogenase phosphatase catalytic subunit 2;PDPC 2
- Observed Band(KD):
- 59kD
- Background:
- This gene is a mitochondrial protein that functions as a phosphatase and is involved in the enzymatic resetting of the pyruvate dehydrogenase complex. Alternative splicing results in multiple transcript variants encoding the same protein. [provided by RefSeq, Aug 2016],
- Function:
- catalytic activity:[Pyruvate dehydrogenase (acetyl-transferring)] phosphate + H(2)O = [pyruvate dehydrogenase (acetyl-transferring)] + phosphate.,cofactor:Binds 2 magnesium ions per subunit.,function:Catalyzes the dephosphorylation and concomitant reactivation of the alpha subunit of the E1 component of the pyruvate dehydrogenase complex.,similarity:Belongs to the PP2C family.,subunit:Heterodimer of a catalytic subunit and a FAD protein of unknown function.,
- Subcellular Location:
- Mitochondrion matrix .
- Expression:
- Brain,
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- Antibody-FAQs
- Products Images
- Western Blot analysis of extracts from K562 cells, using PDP2 Polyclonal Antibody. Secondary antibody(catalog#:RS0002) was diluted at 1:20000
- Immunohistochemical analysis of paraffin-embedded human Gastric adenocarcinoma. 1, Antibody was diluted at 1:200(4° overnight). 2, Tris-EDTA,pH9.0 was used for antigen retrieval. 3,Secondary antibody was diluted at 1:200(room temperature, 45min).