VHX Polyclonal Antibody

    • Catalog No.:YT4877
    • Applications:WB;IHC;IF;ELISA
    • Reactivity:Human;Mouse
      • Target:
      • VHX
      • Gene Name:
      • DUSP22
      • Protein Name:
      • Dual specificity protein phosphatase 22
      • Human Swiss Prot No:
      • Q9NRW4
      • Mouse Swiss Prot No:
      • Q99N11
      • Immunogen:
      • The antiserum was produced against synthesized peptide derived from human DUSP22. AA range:121-170
      • Specificity:
      • VHX Polyclonal Antibody detects endogenous levels of VHX protein.
      • Formulation:
      • Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
      • Source:
      • Polyclonal, Rabbit,IgG
      • Dilution:
      • WB 1:500 - 1:2000. ELISA: 1:10000.. IF 1:50-200
      • Purification:
      • The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
      • Concentration:
      • 1 mg/ml
      • Storage Stability:
      • -15°C to -25°C/1 year(Do not lower than -25°C)
      • Other Name:
      • DUSP22;JSP1;LMWDSP2;MKPX;Dual specificity protein phosphatase 22;JNK-stimulatory phosphatase-1;JSP-1;Low molecular weight dual specificity phosphatase 2;LMW-DSP2;Mitogen-activated protein kinase phosphatase x;MAP kinase phosphatas
      • Observed Band(KD):
      • 21kD
      • Background:
      • catalytic activity:A phosphoprotein + H(2)O = a protein + phosphate.,catalytic activity:Protein tyrosine phosphate + H(2)O = protein tyrosine + phosphate.,function:Activates the Jnk signaling pathway. Dephosphorylates and deactivates p38 and stress-activated protein kinase/c-Jun N-terminal kinase (SAPK/JNK).,similarity:Belongs to the protein-tyrosine phosphatase family. Non-receptor class dual specificity subfamily.,similarity:Contains 1 tyrosine-protein phosphatase domain.,tissue specificity:Ubiquitous. Highest expression seen in heart, placenta, lung, liver, kidney and pancreas.,
      • Function:
      • catalytic activity:A phosphoprotein + H(2)O = a protein + phosphate.,catalytic activity:Protein tyrosine phosphate + H(2)O = protein tyrosine + phosphate.,function:Activates the Jnk signaling pathway. Dephosphorylates and deactivates p38 and stress-activated protein kinase/c-Jun N-terminal kinase (SAPK/JNK).,similarity:Belongs to the protein-tyrosine phosphatase family. Non-receptor class dual specificity subfamily.,similarity:Contains 1 tyrosine-protein phosphatase domain.,tissue specificity:Ubiquitous. Highest expression seen in heart, placenta, lung, liver, kidney and pancreas.,
      • Subcellular Location:
      • Cytoplasm .
      • Expression:
      • Ubiquitous. Highest expression seen in heart, placenta, lung, liver, kidney and pancreas.
      • Products Images
      • Western blot analysis of lysates from RAW264.7 and Jurkat cells, using DUSP22 Antibody. The lane on the right is blocked with the synthesized peptide.
      • Immunohistochemical analysis of paraffin-embedded human tonsil. 1, Antibody was diluted at 1:200(4° overnight). 2, Tris-EDTA,pH9.0 was used for antigen retrieval. 3,Secondary antibody was diluted at 1:200(room temperature, 30min).