VHX Polyclonal Antibody
- Catalog No.:YT4877
- Applications:WB;IHC;IF;ELISA
- Reactivity:Human;Mouse
- Target:
- VHX
- Gene Name:
- DUSP22
- Protein Name:
- Dual specificity protein phosphatase 22
- Human Gene Id:
- 56940
- Human Swiss Prot No:
- Q9NRW4
- Mouse Gene Id:
- 105352
- Mouse Swiss Prot No:
- Q99N11
- Immunogen:
- The antiserum was produced against synthesized peptide derived from human DUSP22. AA range:121-170
- Specificity:
- VHX Polyclonal Antibody detects endogenous levels of VHX protein.
- Formulation:
- Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
- Source:
- Polyclonal, Rabbit,IgG
- Dilution:
- WB 1:500 - 1:2000. ELISA: 1:10000.. IF 1:50-200
- Purification:
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
- Concentration:
- 1 mg/ml
- Storage Stability:
- -15°C to -25°C/1 year(Do not lower than -25°C)
- Other Name:
- DUSP22;JSP1;LMWDSP2;MKPX;Dual specificity protein phosphatase 22;JNK-stimulatory phosphatase-1;JSP-1;Low molecular weight dual specificity phosphatase 2;LMW-DSP2;Mitogen-activated protein kinase phosphatase x;MAP kinase phosphatas
- Observed Band(KD):
- 21kD
- Background:
- catalytic activity:A phosphoprotein + H(2)O = a protein + phosphate.,catalytic activity:Protein tyrosine phosphate + H(2)O = protein tyrosine + phosphate.,function:Activates the Jnk signaling pathway. Dephosphorylates and deactivates p38 and stress-activated protein kinase/c-Jun N-terminal kinase (SAPK/JNK).,similarity:Belongs to the protein-tyrosine phosphatase family. Non-receptor class dual specificity subfamily.,similarity:Contains 1 tyrosine-protein phosphatase domain.,tissue specificity:Ubiquitous. Highest expression seen in heart, placenta, lung, liver, kidney and pancreas.,
- Function:
- catalytic activity:A phosphoprotein + H(2)O = a protein + phosphate.,catalytic activity:Protein tyrosine phosphate + H(2)O = protein tyrosine + phosphate.,function:Activates the Jnk signaling pathway. Dephosphorylates and deactivates p38 and stress-activated protein kinase/c-Jun N-terminal kinase (SAPK/JNK).,similarity:Belongs to the protein-tyrosine phosphatase family. Non-receptor class dual specificity subfamily.,similarity:Contains 1 tyrosine-protein phosphatase domain.,tissue specificity:Ubiquitous. Highest expression seen in heart, placenta, lung, liver, kidney and pancreas.,
- Subcellular Location:
- Cytoplasm .
- Expression:
- Ubiquitous. Highest expression seen in heart, placenta, lung, liver, kidney and pancreas.
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- Antibody-FAQs
- Products Images
- Western blot analysis of lysates from RAW264.7 and Jurkat cells, using DUSP22 Antibody. The lane on the right is blocked with the synthesized peptide.
- Immunohistochemical analysis of paraffin-embedded human tonsil. 1, Antibody was diluted at 1:200(4° overnight). 2, Tris-EDTA,pH9.0 was used for antigen retrieval. 3,Secondary antibody was diluted at 1:200(room temperature, 30min).