TWIK-1 Polyclonal Antibody

    • Catalog No.:YT4786
    • Applications:WB,ELISA
    • Reactivity:Human,Rat
      • Gene Name:
      • KCNK1
      • Protein Name:
      • Potassium channel subfamily K member 1
      • Human Gene Id:
      • 3775
      • Human Swiss Prot No:
      • O00180
      • Mouse Swiss Prot No:
      • O08581
      • Immunogen:
      • The antiserum was produced against synthesized peptide derived from human KCNK1. AA range:287-336
      • Specificity:
      • TWIK-1 Polyclonal Antibody detects endogenous levels of TWIK-1 protein.
      • Formulation:
      • Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
      • Source:
      • Rabbit
      • Dilution:
      • Western Blot: 1/500 - 1/2000. ELISA: 1/40000. Not yet tested in other applications.
      • Purification:
      • The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
      • Concentration:
      • 1 mg/ml
      • Storage Stability:
      • -20°C/1 year
      • Other Name:
      • KCNK1; HOHO1; KCNO1; TWIK1; Potassium channel subfamily K member 1; Inward rectifying potassium channel protein TWIK-1; Potassium channel KCNO1
      • MolecularWeight(Da):
      • 38143
      • Observed Band(KD):
      • 38
      • Background:
      • potassium two pore domain channel subfamily K member 1(KCNK1) Homo sapiens This gene encodes one of the members of the superfamily of potassium channel proteins containing two pore-forming P domains. The product of this gene has not been shown to be a functional channel, however, it may require other non-pore-forming proteins for activity. [provided by RefSeq, Jul 2008],
      • Function:
      • function:Weakly inward rectifying potassium channel.,miscellaneous:Inhibited by barium, quinine, quinidine and internal acidification. Activated by protein kinase C.,similarity:Belongs to the two pore domain potassium channel (TC 1.A.1.8) family.,subunit:Homodimer .,tissue specificity:Widely expressed with high levels in heart and brain and lower levels in placenta, lung, liver and kidney.,
      • Subcellular Location:
      • endosome,plasma membrane,integral component of plasma membrane,voltage-gated potassium channel complex,integral component of membrane,cytoplasmic, membrane-bounded vesicle,apical plasma membrane,cell junction,dendrite,
      • Expression:
      • Brain,Kidney,
      • Products Images
      • Western blot analysis of lysates from Jurkat cells, using KCNK1 Antibody. The lane on the right is blocked with the synthesized peptide.