TSSK 6 Polyclonal Antibody

    • Catalog No.:YT4768
    • Applications:IHC;IF;ELISA
    • Reactivity:Human;Mouse;Rat;
      • Target:
      • TSSK6
      • Gene Name:
      • TSSK6
      • Protein Name:
      • Testis-specific serine/threonine-protein kinase 6
      • Human Swiss Prot No:
      • Q9BXA6
      • Mouse Swiss Prot No:
      • Q925K9
      • Immunogen:
      • Synthesized peptide derived from the Internal region of human TSSK 6.
      • Specificity:
      • TSSK 6 Polyclonal Antibody detects endogenous levels of TSSK 6 protein.
      • Formulation:
      • Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
      • Source:
      • Polyclonal, Rabbit,IgG
      • Dilution:
      • IHC 1:100 - 1:300. ELISA: 1:40000.. IF 1:50-200
      • Purification:
      • The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
      • Concentration:
      • 1 mg/ml
      • Storage Stability:
      • -15°C to -25°C/1 year(Do not lower than -25°C)
      • Other Name:
      • TSSK6;SSTK;FKSG82;Testis-specific serine/threonine-protein kinase 6;TSK-6;TSSK-6;Testis-specific kinase 6;Cancer/testis antigen 72;CT72;Serine/threonine-protein kinase SSTK;Small serine/threonine kinase
      • Molecular Weight(Da):
      • 30kD
      • Background:
      • This intronless gene encodes a member of the CAMK (calcium/calmodulin-dependent) serine/threonine protein kinase family. The encoded kinase has a broad expression pattern but is described as testis-specific due to effects on fertility. Male mice which lack the gene encoding a highly similar protein are sterile and have morphologically abnormal sperm. [provided by RefSeq, Jan 2012],
      • Function:
      • catalytic activity:ATP + a protein = ADP + a phosphoprotein.,cofactor:Magnesium.,function:Required for sperm production and function. Plays a role in DNA condensation during postmeiotic chromatin remodeling.,PTM:Autophosphorylated.,similarity:Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family.,similarity:Contains 1 protein kinase domain.,subunit:Interacts with the heatshock proteins HSPCB, HSPA8 and HAPA1A. These interactions appear to be required for TSSK6 kinase activity.,tissue specificity:Highly expressed in testis. Expressed at lower levels in human colon, small intestine, ovary, prostate, thymus, spleen and peripheral blood leukocytes.,
      • Subcellular Location:
      • nucleus,cytoplasm,
      • Expression:
      • Highly expressed in testis. Expressed at lower levels in colon, small intestine, ovary, prostate, thymus, spleen and peripheral blood leukocytes.
      • Products Images
      • Immunohistochemical analysis of paraffin-embedded human tonsil. 1, Tris-EDTA,pH9.0 was used for antigen retrieval. 2 Antibody was diluted at 1:200(4° overnight.3,Secondary antibody was diluted at 1:200(room temperature, 45min).