Troponin I-C Polyclonal Antibody

  • Catalog No.：YT4747
  • Applications：WB;IHC;IF;ELISA
  • Reactivity：Mouse;Rat
    • Target：
    • Troponin I-C
    • Gene Name：
    • TNNI3
    • Protein Name：
    • Troponin I cardiac muscle
    • Human Swiss Prot No：
    • P19429
    • Immunogen：
    • The antiserum was produced against synthesized peptide derived from mouse TNNI3. AA range:5-54
    • Specificity：
    • Troponin I-C Polyclonal Antibody detects endogenous levels of Troponin I-C protein.
    • Formulation：
    • Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
    • Source：
    • Polyclonal, Rabbit,IgG
    • Dilution：
    • WB 1:500 - 1:2000. IHC 1:100 - 1:300. ELISA: 1:5000.. IF 1:50-200
    • Purification：
    • The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
    • Concentration：
    • 1 mg/ml
    • Storage Stability：
    • -15°C to -25°C/1 year(Do not lower than -25°C)
    • Other Name：
    • TNNI3;TNNC1;Troponin I; cardiac muscle;Cardiac troponin I
    • Observed Band(KD)：
    • 28kD
    • Background：
    • Troponin I (TnI), along with troponin T (TnT) and troponin C (TnC), is one of 3 subunits that form the troponin complex of the thin filaments of striated muscle. TnI is the inhibitory subunit; blocking actin-myosin interactions and thereby mediating striated muscle relaxation. The TnI subfamily contains three genes: tnI-skeletal-fast-twitch, TnI-skeletal-slow-twitch, and TnI-cardiac. This gene encodes the TnI-cardiac protein and is exclusively expressed in cardiac muscle tissues. Mutations in this gene cause familial hypertrophic cardiomyopathy type 7 (CMH7) and familial restrictive cardiomyopathy (RCM).

    Attributes

    • Code：
    • YT4747
    • Size
    • 40μL / 100μL / 200μL
    • Price$：
    • 150 / 280 / 450
    • Delivery：
    • 2024-11-24
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