• Target：
• TRH-R1

• Fields：
• >>Calcium signaling pathway;>>Neuroactive ligand-receptor interaction

• Gene Name：
• TRHR

• Protein Name：
• Thyrotropin-releasing hormone receptor

• Human Gene Id：
• 7201

• Human Swiss Prot No：
• P34981

• Mouse Gene Id：
• 22045

• Mouse Swiss Prot No：
• P21761

• Rat Gene Id：
• 25570

• Rat Swiss Prot No：
• Q01717

• Immunogen：
• The antiserum was produced against synthesized peptide derived from human TRHR. AA range:195-244

• Specificity：
• TRH-R1 Polyclonal Antibody detects endogenous levels of TRH-R1 protein.

• Formulation：
• Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

• Source：
• Polyclonal, Rabbit,IgG

• Dilution：
• WB 1:500 - 1:2000. IF 1:200 - 1:1000. ELISA: 1:20000. Not yet tested in other applications.

• Purification：
• The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

• Concentration：
• 1 mg/ml

• Storage Stability：
• -15°C to -25°C/1 year(Do not lower than -25°C)

• Other Name：
• TRHR;Thyrotropin-releasing hormone receptor;TRH-R;Thyroliberin receptor

• Observed Band(KD)：
• 50kD

• Background：
• This gene encodes a G protein-coupled receptor for thyrotropin-releasing hormone (TRH). Upon binding to TRH, this receptor activates the inositol phospholipid-calcium-protein kinase C transduction pathway. Mutations in this gene have been associated with generalized thyrotropin-releasing hormone resistance. [provided by RefSeq, Sep 2011],

• Function：
• function:Receptor for thyrotropin-releasing hormone. This receptor is mediated by G proteins which activate a phosphatidylinositol-calcium second messenger system.,similarity:Belongs to the G-protein coupled receptor 1 family.,

• Subcellular Location：
• Cell membrane ; Multi-pass membrane protein .

• Expression：
• Brain,Pituitary,Placenta,

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