• Target：
• TAUT

• Gene Name：
• SLC6A6

• Protein Name：
• Sodium- and chloride-dependent taurine transporter

• Human Gene Id：
• 6533

• Human Swiss Prot No：
• P31641

• Mouse Gene Id：
• 21366

• Mouse Swiss Prot No：
• O35316

• Rat Gene Id：
• 29464

• Rat Swiss Prot No：
• P31643

• Immunogen：
• The antiserum was produced against synthesized peptide derived from human SLC6A6. AA range:561-610

• Specificity：
• TAUT Polyclonal Antibody detects endogenous levels of TAUT protein.

• Formulation：
• Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

• Source：
• Polyclonal, Rabbit,IgG

• Dilution：
• WB 1:500 - 1:2000. IHC 1:100 - 1:300. ELISA: 1:40000.. IF 1:50-200

• Purification：
• The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

• Concentration：
• 1 mg/ml

• Storage Stability：
• -15°C to -25°C/1 year(Do not lower than -25°C)

• Other Name：
• SLC6A6;Sodium- and chloride-dependent taurine transporter;Solute carrier family 6 member 6

• Observed Band(KD)：
• 70kD

• Background：
• This gene encodes a multi-pass membrane protein that is a member of a family of sodium and chloride-ion dependent transporters. The encoded protein transports taurine and beta-alanine. There is a pseudogene for this gene on chromosome 21. Alternative splicing results in multiple transcript variants. [provided by RefSeq, May 2013],

• Function：
• function:Required for the uptake of taurine.,PTM:Down-regulated upon Ser-322 phosphorylation.,similarity:Belongs to the sodium:neurotransmitter symporter (SNF) family.,

• Subcellular Location：
• Cell membrane ; Multi-pass membrane protein .

• Expression：
• Expressed abundantly in placenta and skeletal muscle, at intermediate levels in heart, brain, lung, kidney and pancreas and at low levels in liver.

Integrated Single-Cell Transcriptomic Atlas of Human Kidney Endothelial Cells JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY Zhang Ka IF Human kidney tissue

Taurine Inhibits Lung Metastasis in Triple-Negative Breast Cancer by Modulating Macrophage Polarization Through PTEN-PI3K/Akt/mTOR Pathway JOURNAL OF IMMUNOTHERAPY Lin Yufeng IHC Mouse Lung tissue

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