• Target：
• Pax-1

• Gene Name：
• PAX1

• Protein Name：
• Paired box protein Pax-1

• Human Gene Id：
• 5075

• Human Swiss Prot No：
• P15863

• Mouse Swiss Prot No：
• P09084

• Immunogen：
• The antiserum was produced against synthesized peptide derived from human Pax-1. AA range:318-367

• Specificity：
• Pax-1 Polyclonal Antibody detects endogenous levels of Pax-1 protein.

• Formulation：
• Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

• Source：
• Polyclonal, Rabbit,IgG

• Dilution：
• WB 1:500 - 1:2000. IHC 1:100 - 1:300. ELISA: 1:5000.. IF 1:50-200

• Purification：
• The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

• Concentration：
• 1 mg/ml

• Storage Stability：
• -15°C to -25°C/1 year(Do not lower than -25°C)

• Other Name：
• PAX1;HUP48;Paired box protein Pax-1;HuP48

• Observed Band(KD)：
• 36kD

• Background：
• This gene is a member of the paired box (PAX) family of transcription factors. Members of the PAX family typically contain a paired box domain and a paired-type homeodomain. These genes play critical roles during fetal development. This gene plays a role in pattern formation during embryogenesis and may be essential for development of the vertebral column. This gene is silenced by methylation in ovarian and cervical cancers and may be a tumor suppressor gene. Mutations in this gene are also associated with vertebral malformations. [provided by RefSeq, Mar 2012],

• Function：
• function:This protein is a transcriptional activator. It may play a role in the formation of segmented structures of the embryo. May play an important role in the normal development of the vertebral column.,similarity:Contains 1 paired domain.,

• Subcellular Location：
• Nucleus.

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