p39 Polyclonal Antibody
- Catalog No.:YT3515
- Applications:WB;IHC;IF;ELISA
- Reactivity:Human;Mouse
- Target:
- p39
- Gene Name:
- CDK5R2
- Protein Name:
- Cyclin-dependent kinase 5 activator 2
- Human Gene Id:
- 8941
- Human Swiss Prot No:
- Q13319
- Mouse Swiss Prot No:
- O35926
- Immunogen:
- The antiserum was produced against synthesized peptide derived from human CDK5R2. AA range:81-130
- Specificity:
- p39 Polyclonal Antibody detects endogenous levels of p39 protein.
- Formulation:
- Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
- Source:
- Polyclonal, Rabbit,IgG
- Dilution:
- WB 1:500 - 1:2000. IHC 1:100 - 1:300. ELISA: 1:20000.. IF 1:50-200
- Purification:
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
- Concentration:
- 1 mg/ml
- Storage Stability:
- -15°C to -25°C/1 year(Do not lower than -25°C)
- Other Name:
- CDK5R2;NCK5AI;Cyclin-dependent kinase 5 activator 2;CDK5 activator 2;Cyclin-dependent kinase 5 regulatory subunit 2;p39;p39I
- Observed Band(KD):
- 40kD
- Background:
- The protein encoded by this gene is a neuron-specific activator of CDK5 kinase. It associates with CDK5 to form an active kinase. This protein and neuron-specific CDK5 activator CDK5R1/p39NCK5A both share limited similarity to cyclins, and thus may define a distinct family of cyclin-dependent kinase activating proteins. [provided by RefSeq, Jul 2008],
- Function:
- function:Activator of CDK5/TPKII.,similarity:Belongs to the cyclin-dependent kinase 5 activator family.,subunit:Heterodimer of a catalytic subunit and a regulatory subunit.,tissue specificity:Brain and neuron specific.,
- Subcellular Location:
- Cell membrane ; Lipid-anchor ; Cytoplasmic side .
- Expression:
- Brain and neuron specific.
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- Antibody-FAQs
- Products Images
- Western Blot analysis of various cells using p39 Polyclonal Antibody cells nucleus extracted by Minute TM Cytoplasmic and Nuclear Fractionation kit (SC-003,Inventbiotech,MN,USA).
- Immunohistochemical analysis of paraffin-embedded Human brain. Antibody was diluted at 1:100(4° overnight). High-pressure and temperature Tris-EDTA,pH8.0 was used for antigen retrieval. Negetive contrl (right) obtaned from antibody was pre-absorbed by immunogen peptide.
- Western blot analysis of lysates from HUVEC cells, using CDK5R2 Antibody. The lane on the right is blocked with the synthesized peptide.