• Target：
• NT-4

• Fields：
• >>MAPK signaling pathway;>>Ras signaling pathway;>>PI3K-Akt signaling pathway;>>Neurotrophin signaling pathway

• Gene Name：
• NTF4

• Protein Name：
• Neurotrophin-4

• Human Gene Id：
• 4909

• Human Swiss Prot No：
• P34130

• Mouse Gene Id：
• 78405

• Mouse Swiss Prot No：
• Q80VU4

• Rat Gene Id：
• 25730

• Rat Swiss Prot No：
• P34131

• Immunogen：
• The antiserum was produced against synthesized peptide derived from human NT-4. AA range:71-120

• Specificity：
• NT-4 Polyclonal Antibody detects endogenous levels of NT-4 protein.

• Formulation：
• Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

• Source：
• Polyclonal, Rabbit,IgG

• Dilution：
• IHC 1:100 - 1:300. ELISA: 1:10000.. IF 1:50-200

• Purification：
• The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

• Concentration：
• 1 mg/ml

• Storage Stability：
• -15°C to -25°C/1 year(Do not lower than -25°C)

• Other Name：
• NTF4;NTF5;Neurotrophin-4;NT-4;Neurotrophin-5;NT-5;Neutrophic factor 4

• Molecular Weight(Da)：
• 22kD

• Background：
• This gene is a member of a family of neurotrophic factors, neurotrophins, that control survival and differentiation of mammalian neurons. The expression of this gene is ubiquitous and less influenced by environmental signals. While knock-outs of other neurotrophins including nerve growth factor, brain-derived neurotrophic factor, and neurotrophin 3 prove lethal during early postnatal development, NTF5-deficient mice only show minor cellular deficits and develop normally to adulthood. [provided by RefSeq, Jul 2008],

• Function：
• function:Target-derived survival factor for peripheral sensory sympathetic neurons.,similarity:Belongs to the NGF-beta family.,tissue specificity:Highest levels in prostate, lower levels in thymus, placenta, and skeletal muscle. Expressed in embryonic and adult tissues.,

• Subcellular Location：
• Secreted.

• Expression：
• Highest levels in prostate, lower levels in thymus, placenta, and skeletal muscle. Expressed in embryonic and adult tissues.

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