• Target：
• NPY5-R

• Fields：
• >>Neuroactive ligand-receptor interaction

• Gene Name：
• NPY5R

• Protein Name：
• Neuropeptide Y receptor type 5

• Human Gene Id：
• 4889

• Human Swiss Prot No：
• Q15761

• Mouse Gene Id：
• 18168

• Mouse Swiss Prot No：
• O70342

• Rat Gene Id：
• 25340

• Rat Swiss Prot No：
• Q63634

• Immunogen：
• The antiserum was produced against synthesized peptide derived from human NPY5R. AA range:221-270

• Specificity：
• NPY5-R Polyclonal Antibody detects endogenous levels of NPY5-R protein.

• Formulation：
• Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

• Source：
• Polyclonal, Rabbit,IgG

• Dilution：
• WB 1:500 - 1:2000. IHC 1:100 - 1:300. IF 1:200 - 1:1000. ELISA: 1:20000. Not yet tested in other applications.

• Purification：
• The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

• Concentration：
• 1 mg/ml

• Storage Stability：
• -15°C to -25°C/1 year(Do not lower than -25°C)

• Other Name：
• NPY5R;NPYR5;Neuropeptide Y receptor type 5;NPY5-R;NPY-Y5 receptor;NPYY5-R;Y5 receptor

• Observed Band(KD)：
• 48kD

• Background：
• The protein encoded by this gene is a receptor for neuropeptide Y and peptide YY. The encoded protein appears to be involved in regulating food intake, with defects in this gene being associated with eating disorders. Also, the encoded protein is involved in a pathway that protects neuroblastoma cells from chemotherapy-induced cell death, providing a possible therapeutic target against neuroblastoma. Three transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Nov 2015],

• Function：
• function:Receptor for neuropeptide Y and peptide YY. The activity of this receptor is mediated by G proteins that inhibit adenylate cyclase activity. Seems to be associated with food intake. Could be involved in feeding disorders.,similarity:Belongs to the G-protein coupled receptor 1 family.,tissue specificity:Brain; hypothalamus.,

• Subcellular Location：
• Cell membrane; Multi-pass membrane protein.

• Expression：
• Brain; hypothalamus.

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