• Target：
• Neuron Navigator 1

• Gene Name：
• NAV1

• Protein Name：
• Neuron navigator 1

• Human Gene Id：
• 89796

• Human Swiss Prot No：
• Q8NEY1

• Mouse Gene Id：
• 215690

• Mouse Swiss Prot No：
• Q8CH77

• Immunogen：
• Synthesized peptide derived from Neuron Navigator 1 . at AA range: 510-590

• Specificity：
• Neuron Navigator 1 Polyclonal Antibody detects endogenous levels of Neuron Navigator 1 protein.

• Formulation：
• Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

• Source：
• Polyclonal, Rabbit,IgG

• Dilution：
• IHC 1:100 - 1:300. ELISA: 1:40000.. IF 1:50-200

• Purification：
• The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

• Concentration：
• 1 mg/ml

• Storage Stability：
• -15°C to -25°C/1 year(Do not lower than -25°C)

• Other Name：
• NAV1;KIAA1151;KIAA1213;POMFIL3;STEERIN1;Neuron navigator 1;Pore membrane and/or filament-interacting-like protein 3;Steerin-1;Unc-53 homolog 1;unc53H1

• Observed Band(KD)：
• 200kD

• Background：
• This gene belongs to the neuron navigator family and is expressed predominantly in the nervous system. The encoded protein contains coiled-coil domains and a conserved AAA domain characteristic for ATPases associated with a variety of cellular activities. This gene is similar to unc-53, a Caenorhabditis elegans gene involved in axon guidance. The exact function of this gene is not known, but it is thought to play a role in in neuronal development and regeneration. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Nov 2009],

• Function：
• developmental stage:Expressed in fetal brain and heart.,function:May be involved in neuronal migration.,similarity:Belongs to the Nav/unc-53 family.,subcellular location:Associates with a subset of microtubule plus ends. Enriched in neuronal growth cones.,subunit:Interacts with tubulin.,tissue specificity:Broadly expressed at low levels. Expressed at high levels in heart, skeletal muscle and placenta.,

• Subcellular Location：
• Cytoplasm, cytoskeleton . Associates with a subset of microtubule plus ends. Enriched in neuronal growth cones (By similarity). .

• Expression：
• Broadly expressed at low levels. Expressed at high levels in heart, skeletal muscle and placenta.

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