• Target：
• Neuroglycan C

• Gene Name：
• CSPG5

• Protein Name：
• Chondroitin sulfate proteoglycan 5

• Human Gene Id：
• 10675

• Human Swiss Prot No：
• O95196

• Mouse Gene Id：
• 29873

• Mouse Swiss Prot No：
• Q71M36

• Rat Gene Id：
• 50568

• Rat Swiss Prot No：
• Q9ERQ6

• Immunogen：
• The antiserum was produced against synthesized peptide derived from human CSPG5. AA range:211-260

• Specificity：
• Neuroglycan C Polyclonal Antibody detects endogenous levels of Neuroglycan C protein.

• Formulation：
• Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

• Source：
• Polyclonal, Rabbit,IgG

• Dilution：
• WB 1:500-2000;IHC 1:50-300

• Purification：
• The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

• Concentration：
• 1 mg/ml

• Storage Stability：
• -15°C to -25°C/1 year(Do not lower than -25°C)

• Other Name：
• CSPG5;CALEB;NGC;Chondroitin sulfate proteoglycan 5;Acidic leucine-rich EGF-like domain-containing brain protein;Neuroglycan C

• Observed Band(KD)：
• 60kD

• Background：
• The protein encoded by this gene is a proteoglycan that may function as a neural growth and differentiation factor. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, May 2011],

• Function：
• developmental stage:Expressed in brain of 3 months, 5 and 10-year-old individuals.,function:May function as a growth and differentiation factor involved in neuritogenesis. May induce ERBB3 activation.,miscellaneous:Different forms of various molecular weight have been observed. Such forms are possibly due to different levels of glycosylation, phosphorylation and/or protein cleavage.,PTM:N-glycosylated.,PTM:O-glycosylated; contains chondroitin sulfate glycans. Part-time proteoglycan, expressed in part as a proteoglycan exhibiting chondroitin sulfate glycans and in part as a non-proteoglycan form. The relative amount of both forms depends on tissues and tissues maturation.,PTM:Phosphorylated; in intracellular and extracellular parts.,similarity:Contains 1 EGF-like domain.,subcellular location:In neurons, localizes to synaptic junctions (By similarity). Also detected in the endoplasmic reti

• Subcellular Location：
• Cell membrane ; Single-pass type I membrane protein . Cell junction, synapse, synaptic cell membrane ; Single-pass type I membrane protein . Endoplasmic reticulum membrane ; Single-pass type I membrane protein . Golgi apparatus membrane ; Single-pass type I membrane protein . Cell surface . In neurons, localizes to synaptic junctions. Also detected in the endoplasmic reticulum and the Golgi. Partially enriched in lipid rafts. .

• Expression：
• Restricted to brain (at protein level).

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