• Target：
• Myomesin-2

• Gene Name：
• MYOM2

• Protein Name：
• Myomesin-2

• Human Gene Id：
• 9172

• Human Swiss Prot No：
• P54296

• Immunogen：
• The antiserum was produced against synthesized peptide derived from human MYOM2. AA range:612-661

• Specificity：
• Myomesin-2 Polyclonal Antibody detects endogenous levels of Myomesin-2 protein.

• Formulation：
• Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

• Source：
• Polyclonal, Rabbit,IgG

• Dilution：
• WB 1:500-2000;IHC 1:50-300; ELISA 2000-20000

• Purification：
• The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

• Concentration：
• 1 mg/ml

• Storage Stability：
• -15°C to -25°C/1 year(Do not lower than -25°C)

• Other Name：
• MYOM2;Myomesin-2;165 kDa connectin-associated protein;165 kDa titin-associated protein;M-protein;Myomesin family member 2

• Observed Band(KD)：
• 165kD

• Background：
• The giant protein titin, together with its associated proteins, interconnects the major structure of sarcomeres, the M bands and Z discs. The C-terminal end of the titin string extends into the M line, where it binds tightly to M-band constituents of apparent molecular masses of 190 kD and 165 kD. The predicted MYOM2 protein contains 1,465 amino acids. Like MYOM1, MYOM2 has a unique N-terminal domain followed by 12 repeat domains with strong homology to either fibronectin type III or immunoglobulin C2 domains. Protein sequence comparisons suggested that the MYOM2 protein and bovine M protein are identical. [provided by RefSeq, Jul 2008],

• Function：
• function:Major component of the vertebrate myofibrillar M band. Binds myosin, titin, and light meromyosin. This binding is dose dependent.,similarity:Contains 5 fibronectin type-III domains.,similarity:Contains 5 Ig-like C2-type (immunoglobulin-like) domains.,subunit:Interacts with TTN/titin.,

• Subcellular Location：
• Cytoplasm, myofibril, sarcomere, M line .

• Expression：
• PNS,Skeletal muscle,

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