• Target：
• MIP-T3

• Gene Name：
• TRAF3IP1

• Protein Name：
• TRAF3-interacting protein 1

• Human Gene Id：
• 26146

• Human Swiss Prot No：
• Q8TDR0

• Mouse Swiss Prot No：
• Q149C2

• Immunogen：
• The antiserum was produced against synthesized peptide derived from human MIPT3. AA range:221-270

• Specificity：
• MIP-T3 Polyclonal Antibody detects endogenous levels of MIP-T3 protein.

• Formulation：
• Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

• Source：
• Polyclonal, Rabbit,IgG

• Dilution：
• WB 1:500-2000 IHC 1:100 - 1:300. IF 1:200 - 1:1000. ELISA: 1:10000. Not yet tested in other applications.

• Purification：
• The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

• Concentration：
• 1 mg/ml

• Storage Stability：
• -15°C to -25°C/1 year(Do not lower than -25°C)

• Other Name：
• TRAF3IP1;MIPT3;TRAF3-interacting protein 1;Interleukin-13 receptor alpha 1-binding protein 1;Microtubule-interacting protein associated with TRAF3;MIP-T3

• Observed Band(KD)：
• 78kD

• Background：
• function:Play an inhibitory role on IL13 signaling by binding to IL13RA1. Involved in suppression of IL13-induced STAT6 phosphorylation, transcriptional activity and DNA-binding. Recruits TRAF3 and DISC1 to the microtubules.,similarity:Belongs to the TRAF3IP1 family.,subcellular location:Microtubules.,subunit:Interacts with IL13RA1. Binds to microtubules, TRAF3 and DISC1.,tissue specificity:Ubiquitous.,

• Function：
• function:Play an inhibitory role on IL13 signaling by binding to IL13RA1. Involved in suppression of IL13-induced STAT6 phosphorylation, transcriptional activity and DNA-binding. Recruits TRAF3 and DISC1 to the microtubules.,similarity:Belongs to the TRAF3IP1 family.,subcellular location:Microtubules.,subunit:Interacts with IL13RA1. Binds to microtubules, TRAF3 and DISC1.,tissue specificity:Ubiquitous.,

• Subcellular Location：
• Cytoplasm, cytoskeleton . Cell projection, cilium . Cytoplasm, cytoskeleton, cilium axoneme . Cytoplasm, cytoskeleton, cilium basal body . Microtubules (PubMed:12935900). In the cilium, it is observed at the ciliary base, ciliary transition zone and ciliary tip (PubMed:26487268). .

• Expression：
• Ubiquitous.

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