Formin 2 Polyclonal Antibody

    • Catalog No.:YT1737
    • Applications:IHC-p,ELISA
    • Reactivity:Human,Mouse
      • Gene Name:
      • FMN2
      • Protein Name:
      • Formin-2
      • Human Swiss Prot No:
      • Q9NZ56
      • Mouse Swiss Prot No:
      • Q9JL04
      • Immunogen:
      • The antiserum was produced against synthesized peptide derived from human FMN2. AA range:1541-1590
      • Specificity:
      • Formin 2 Polyclonal Antibody detects endogenous levels of Formin 2 protein.
      • Formulation:
      • Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
      • Source:
      • Rabbit
      • Dilution:
      • Immunohistochemistry: 1/100 - 1/300. ELISA: 1/40000. Not yet tested in other applications.
      • Purification:
      • The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
      • Concentration:
      • 1 mg/ml
      • Storage Stability:
      • -20°C/1 year
      • Other Name:
      • FMN2; Formin-2
      • MolecularWeight(Da):
      • 180106
      • Background:
      • formin 2(FMN2) Homo sapiens This gene is a member of the formin homology protein family. The encoded protein is thought to have essential roles in organization of the actin cytoskeleton and in cell polarity. Mutations in this gene have been associated with mental retardation autosomal recessive 47 (MRT47). Alternatively spliced transcript variants have been identified. [provided by RefSeq, Mar 2015],
      • Function:
      • PTM:Phosphorylated upon DNA damage, probably by ATM or ATR.,sequence caution:Contaminating sequence. Sequence of unknown origin in the C-terminal part.,similarity:Belongs to the formin homology family. Cappuccino subfamily.,similarity:Contains 1 FH1 (formin homology 1) domain.,similarity:Contains 1 FH2 (formin homology 2) domain.,tissue specificity:Expressed almost exclusively in the developing and mature central nervous system.,
      • Subcellular Location:
      • nucleolus,endoplasmic reticulum membrane,spindle,cytosol,actin filament,plasma membrane,microvillus,cell cortex,actin cytoskeleton,cytoplasmic vesicle membrane,perinuclear region of cytoplasm,
      • Expression:
      • Brain,Hypothalamus,PCR rescued clones,
      • Products Images
      • Immunohistochemistry analysis of paraffin-embedded human brain tissue, using FMN2 Antibody. The picture on the right is blocked with the synthesized peptide.