• Protein Name：
• AIF1 G1 IBA1

• Sequence：
• Allograft inflammatory factor 1 (AIF-1) (Ionized calcium-binding adapter molecule 1) (Protein G1)

• Human Gene Id：
• 199

• Human Swiss Prot No：
• P55008

• Mouse Gene Id：
• 11629

• Mouse Swiss Prot No：
• O70200

• Rat Gene Id：
• 29427

• Rat Swiss Prot No：
• P55009

• Specificity：
• endogenous

• Formulation：
• PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA

• Source：
• Monoclonal, rabbit, IgG, Kappa

• Dilution：
• IHC 1:2000-1:4000,WB 1:1000-1:5000,IF 1:200-1:1000,ELISA 1:5000-1:20000,IP 1:50-1:200,

• Purification：
• Protein A

• Storage Stability：
• -15°C to -25°C/1 year(Do not lower than -25°C)

• Other Name：
• AIF 1;AIF-1;Aif1;AIF1 protein;AIF1_HUMAN;Allograft inflammatory factor 1;Allograft inflammatory factor 1 splice variant G;allograft inflammatory factor-1 splice variant Hara-1;balloon angioplasty responsive transcription;BART 1;G1;G1 putative splice variant of allograft inflamatory factor 1;IBA 1;IBA1;interferon gamma responsive transcript;Interferon responsive transcript 1;interferon responsive transcript factor 1;Ionized calcium binding adapter molecule 1;Ionized calcium-binding adapter molecule 1;ionized calcium-binding adapter molecule;IRT 1;IRT1;Microglia response factor;MRF1;Protein g1;

• Molecular Weight(Da)：
• 16kD

• Observed Band(KD)：
• 16kD

• Background：
• This gene encodes a protein that binds actin and calcium. This gene is induced by cytokines and interferon and may promote macrophage activation and growth of vascular smooth muscle cells and T-lymphocytes. Polymorphisms in this gene may be associated with systemic sclerosis. Alternative splicing results in multiple transcript variants, but the full-length and coding nature of some of these variants is not certain. [provided by RefSeq, Jan 2016],

• Function：
• function:May play a role in macrophage activation and function.,PTM:Phosphorylated on serine residues.,similarity:Contains 2 EF-hand domains.,

• Subcellular Location：
• Cytoplasm

• Expression：
• Detected in T-lymphocytes and peripheral blood mononuclear cells.

The toxic influence of dibromoacetic acid on the hippocampus and pre-frontal cortex of rat: involvement of neuroinflammation response and oxidative stress. METABOLIC BRAIN DISEASE Metab Brain Dis. 2017 Dec;32(6):2009-2019 WB Rat 1:800 Pre-frontal cortical,hippocampal tissues

A novel phthalein component ameliorates neuroinflammation and cognitive dysfunction by suppressing the CXCL12/CXCR4 axis in rats with vascular dementia JOURNAL OF ETHNOPHARMACOLOGY Kai-Ting Ma IF Rat 1:300 brain tissue

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