FABP4 (PT0176R) PT® Rabbit mAb
- Catalog No.:YM8108
- Applications:WB;IHC;IF;IP;ELISA
- Reactivity:Human; Mouse; Rat;
- Target:
- A-FABP
- Fields:
- >>PPAR signaling pathway;>>Regulation of lipolysis in adipocytes
- Gene Name:
- FABP4
- Protein Name:
- A-FABP
- Human Gene Id:
- 2167
- Human Swiss Prot No:
- P15090
- Mouse Gene Id:
- 11770
- Mouse Swiss Prot No:
- P04117
- Rat Swiss Prot No:
- P70623
- Specificity:
- endogenous
- Formulation:
- PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
- Source:
- Monoclonal, rabbit, IgG, Kappa
- Dilution:
- IHC 1:200-1000,WB 1:1000-5000,IF 1:200-1000,ELISA 1:5000-20000,IP 1:50-200
- Purification:
- Protein A
- Storage Stability:
- -15°C to -25°C/1 year(Do not lower than -25°C)
- Other Name:
- Fatty acid-binding protein, adipocyte (Adipocyte lipid-binding protein;ALBP;Adipocyte-type fatty acid-binding protein;A-FABP;AFABP;Fatty acid-binding protein 4)
- Molecular Weight(Da):
- 15kD
- Observed Band(KD):
- 15kD
- Background:
- FABP4 encodes the fatty acid binding protein found in adipocytes. Fatty acid binding proteins are a family of small, highly conserved, cytoplasmic proteins that bind long-chain fatty acids and other hydrophobic ligands. It is thought that FABPs roles include fatty acid uptake, transport, and metabolism. [provided by RefSeq, Jul 2008],
- Function:
- domain:Forms a beta-barrel structure that accommodates hydrophobic ligands in its interior.,function:Lipid transport protein in adipocytes. Binds both long chain fatty acids and retinoic acid. Delivers long-chain fatty acids and retinoic acid to their cognate receptors in the nucleus.,similarity:Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family.,subcellular location:Depending on the nature of the ligand, a conformation change exposes a nuclear localization motif and the protein is transported into the nucleus. Subject to constitutive nuclear export.,subunit:Homodimer. Interacts with PPARG (By similarity). Monomer.,
- Subcellular Location:
- Cytoplasm
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- Antibody-FAQs
- Products Images
- Various whole cell lysates were separated by 4-20% SDS-PAGE, and the membrane was blotted with anti-FABP4 (PT0176R) antibody. The HRP-conjugated Goat anti-Rabbit IgG(H + L) antibody was used to detect the antibody. Lane 1: Rat heart Lane 2: RT4 Predicted band size: 15kDa Observed band size: 15kDa
- Human breast carcinoma was stained with Anti-FABP4 (PT0176R) rabbit antibody
- Mouse pancreas was stained with Anti-FABP4 (PT0176R) rabbit antibody
- Rat pancreas was stained with Anti-FABP4 (PT0176R) rabbit antibody
- Rat pancreas was stained with anti-FABP4 (PT0176R) rabbit antibody