S100A6 (ABT-S100A6) mouse mAb

    • Catalog No.:YM6668
    • Applications:IHC;ELISA
    • Reactivity:Human
      • Target:
      • S100A6
      • Gene Name:
      • S100A6 CACY
      • Protein Name:
      • S100A6
      • Human Gene Id:
      • 6277
      • Human Swiss Prot No:
      • P06703
      • Immunogen:
      • Synthesized peptide derived from human S100A6 AA range: 50-90
      • Specificity:
      • This antibody detects endogenous levels of human S100A6. Heat-induced epitope retrieval (HIER) TRIS-EDTA of pH8.0 was highly recommended as antigen repair method in paraffin section. The antibody was
      • Formulation:
      • Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
      • Source:
      • Mouse, Monoclonal/IgG1, Kappa
      • Dilution:
      • IHC 1:200-400, ELISA 1:5000-20000
      • Purification:
      • The antibody was affinity-purified from mouse ascites by affinity-chromatography using specific immunogen.
      • Storage Stability:
      • -15°C to -25°C/1 year(Do not lower than -25°C)
      • Background:
      • S100 calcium binding protein A6(S100A6) Homo sapiens The protein encoded by this gene is a member of the S100 family of proteins containing 2 EF-hand calcium-binding motifs. S100 proteins are localized in the cytoplasm and/or nucleus of a wide range of cells, and involved in the regulation of a number of cellular processes such as cell cycle progression and differentiation. S100 genes include at least 13 members which are located as a cluster on chromosome 1q21. This protein may function in stimulation of Ca2+-dependent insulin release, stimulation of prolactin secretion, and exocytosis. Chromosomal rearrangements and altered expression of this gene have been implicated in melanoma. [provided by RefSeq, Jul 2008],
      • Function:
      • induction:Preferentially expressed when quiescent fibroblasts are stimulated to proliferate. It is inducible by growth factors and overexpressed in acute myeloid leukemias.,miscellaneous:This protein co-purified with the prolactin receptor.,PTM:The N-terminus is blocked.,similarity:Belongs to the S-100 family.,similarity:Contains 2 EF-hand domains.,subunit:Homodimer, antiparallel. Interacts with SUGT1.,
      • Subcellular Location:
      • Nuclear, Cytoplasmic
      • Expression:
      • Brain,Fibroblast,Placenta,Platelet,
      • Products Images
      • Human malignant melanoma tissue was stained with Anti-S100A6 (ABT-S100A6) Antibody
      • Human prostate tissue was stained with Anti-S100A6 (ABT-S100A6) Antibody
      • Human renal clear cell carcinoma tissue was stained with Anti-S100A6 (ABT-S100A6) Antibody
      • Human serous papillary adenocarcinoma of ovary tissue was stained with Anti-S100A6 (ABT-S100A6) Antibody
      • Human testis tissue was stained with Anti-S100A6 (ABT-S100A6) Antibody