S100A6(PT2233) mouse mAb

    • Catalog No.:YM6651
    • Applications:IHC-p
    • Reactivity:Human
      • Gene Name:
      • S100A6 CACY
      • Protein Name:
      • Protein S100-A6 (Calcyclin) (Growth factor-inducible protein 2A9) (MLN 4) (Prolactin receptor-associated protein) (PRA) (S100 calcium-binding protein A6)
      • Human Gene Id:
      • 6277
      • Human Swiss Prot No:
      • P06703
      • Immunogen:
      • Synthesized peptide derived from human S100A6
      • Specificity:
      • This antibody detects endogenous levels of human Protein S100-A6 (Calcyclin) (Growth factor-inducible protein 2A9) (MLN 4) (Prolactin receptor-associated protein) (PRA) (S100 calcium-binding protein A
      • Formulation:
      • Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
      • Source:
      • Mouse/IgG1, Kappa
      • Dilution:
      • WB 500-2000 IHC-p 1:100-500
      • Purification:
      • The antibody was affinity-purified from mouse ascites by affinity-chromatography using specific immunogen.
      • Concentration:
      • 1 mg/ml
      • Storage Stability:
      • -20°C/1 year
      • Background:
      • S100 calcium binding protein A6(S100A6) Homo sapiens The protein encoded by this gene is a member of the S100 family of proteins containing 2 EF-hand calcium-binding motifs. S100 proteins are localized in the cytoplasm and/or nucleus of a wide range of cells, and involved in the regulation of a number of cellular processes such as cell cycle progression and differentiation. S100 genes include at least 13 members which are located as a cluster on chromosome 1q21. This protein may function in stimulation of Ca2+-dependent insulin release, stimulation of prolactin secretion, and exocytosis. Chromosomal rearrangements and altered expression of this gene have been implicated in melanoma. [provided by RefSeq, Jul 2008],
      • Function:
      • induction:Preferentially expressed when quiescent fibroblasts are stimulated to proliferate. It is inducible by growth factors and overexpressed in acute myeloid leukemias.,miscellaneous:This protein co-purified with the prolactin receptor.,PTM:The N-terminus is blocked.,similarity:Belongs to the S-100 family.,similarity:Contains 2 EF-hand domains.,subunit:Homodimer, antiparallel. Interacts with SUGT1.,
      • Subcellular Location:
      • Nuclear, Cytoplasmic
      • Expression:
      • Brain,Fibroblast,Placenta,Platelet,
      • Products Images
      • Immunohistochemical analysis of paraffin-embedded human Pancreatic adenocarcinoma. 1,S100A6 Antibody was diluted at 1:200(4°,overnight). 2, EDTA pH 8.0 was used for antigen retrieval
      • Immunohistochemical analysis of paraffin-embedded human Prostate. 1,S100A6 Antibody was diluted at 1:200(4°,overnight). 2, EDTA pH 8.0 was used for antigen retrieval