N-Cadherin (ABT-CDH2) mouse mAb

    • Catalog No.:YM6590
    • Applications:IHC-p,WB
    • Reactivity:Human
      • Gene Name:
      • CDH2 CDHN NCAD
      • Protein Name:
      • Cadherin-2 (CDw325) (Neural cadherin) (N-cadherin) (CD antigen CD325)
      • Human Gene Id:
      • 1000
      • Human Swiss Prot No:
      • P19022
      • Immunogen:
      • Synthesized peptide derived from human N-Cadherin
      • Specificity:
      • This antibody detects endogenous levels of human N-Cadherin. Heat-induced epitope retrieval (HIER) Citrate buffer of pH6.0 was highly recommended as antigen repair method in paraffin section
      • Formulation:
      • Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
      • Source:
      • Mouse/IgG2b, Kappa
      • Dilution:
      • IHC-p 1:100-500,WB 1:500-2000
      • Purification:
      • The antibody was affinity-purified from mouse ascites by affinity-chromatography using specific immunogen.
      • Concentration:
      • 1 mg/ml
      • Storage Stability:
      • -20°C/1 year
      • Background:
      • cadherin 2(CDH2) Homo sapiens This gene encodes a classical cadherin and member of the cadherin superfamily. Alternative splicing results in multiple transcript variants, at least one of which encodes a preproprotein is proteolytically processed to generate a calcium-dependent cell adhesion molecule and glycoprotein. This protein plays a role in the establishment of left-right asymmetry, development of the nervous system and the formation of cartilage and bone. [provided by RefSeq, Nov 2015],
      • Function:
      • function:Cadherins are calcium dependent cell adhesion proteins. They preferentially interact with themselves in a homophilic manner in connecting cells; cadherins may thus contribute to the sorting of heterogeneous cell types. CDH2 may be involved in neuronal recognition mechanism.,similarity:Contains 5 cadherin domains.,subunit:Interacts with CDCP1.,
      • Subcellular Location:
      • Membranous
      • Expression:
      • Brain,Epithelium,Liver,
      • Products Images
      • Immunohistochemical analysis of paraffin-embedded Fallopian tube. 1, Antibody was diluted at 1:200(4°,overnight). 2, Citrate buffer of pH6.0 was used for antigen retrieval. 3,Secondary antibody was diluted at 1:200(room temperature, 30min).
      • Immunohistochemical analysis of paraffin-embedded Liver. 1, Antibody was diluted at 1:200(4°,overnight). 2, Citrate buffer of pH6.0 was used for antigen retrieval. 3,Secondary antibody was diluted at 1:200(room temperature, 30min).
      • Immunohistochemical analysis of paraffin-embedded Liver. 1, Antibody was diluted at 1:200(4°,overnight). 2, Citrate buffer of pH6.0 was used for antigen retrieval. 3,Secondary antibody was diluted at 1:200(room temperature, 30min).
      • Western blot analysis of N-CadherinAntibody at 1:1000 dilution.