Tyrosinase(PT1611) mouse mAb

    • Catalog No.:YM6564
    • Applications:IHC-p
    • Reactivity:Human
    • Description
    • Gene Name:
    • TYR
    • Protein Name:
    • Tyrosinase (EC 1.14.18.1) (LB24-AB) (Monophenol monooxygenase) (SK29-AB) (Tumor rejection antigen AB)
    • Human Gene Id:
    • 7299
    • Human Swiss Prot No:
    • P14679
    • Immunogen:
    • Synthesized peptide derived from human Tyrosinase
    • Specificity:
    • This antibody detects endogenous levels of human Tyrosinase (EC 1.14.18.1) (LB24-AB) (Monophenol monooxygenase) (SK29-AB) (Tumor rejection antigen AB)
    • Formulation:
    • Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
    • Source:
    • Mouse/IgM, Kappa
    • Dilution:
    • IHC-p 1:100-500
    • Purification:
    • The antibody was affinity-purified from mouse ascites by affinity-chromatography using specific immunogen.
    • Concentration:
    • 1 mg/ml
    • Storage Stability:
    • -20°C/1 year
    • Background:
    • The enzyme encoded by TYR catalyzes the first 2 steps, and at least 1 subsequent step, in the conversion of tyrosine to melanin. The enzyme has both tyrosine hydroxylase and dopa oxidase catalytic activities, and requires copper for function. Mutations in this gene result in oculocutaneous albinism, and nonpathologic polymorphisms result in skin pigmentation variation. The human genome contains a pseudogene similar to the 3' half of this gene.
    • Function:
    • tyrosine metabolic process, melanin metabolic process, melanin biosynthetic process from tyrosine, eye pigment biosynthetic process, sensory perception, visual perception, aromatic amino acid family metabolic process, secondary metabolic process, melanin biosynthetic process, pigment metabolic process, eye pigment metabolic process,pigmentation, pigment biosynthetic process, pigmentation during development, eye pigmentation, neurological system process, cognition, sensory perception of light stimulus, oxidation reduction,
    • Products Images
    • Immunohistochemical analysis of paraffin-embedded human Hemangiosarcoma. 1,Tyrosinase Antibody was diluted at 1:200(4°,overnight). 2, EDTA pH 8.0 was used for antigen retrieval
    • Immunohistochemical analysis of paraffin-embedded human hemangiosarcoma. 1,Tyrosinase Antibody was diluted at 1:200(4°,overnight). 2, EDTA pH 8.0 was used for antigen retrieval
    • Immunohistochemical analysis of paraffin-embedded human Malignant melanoma. 1,Tyrosinase Antibody was diluted at 1:200(4°,overnight). 2, EDTA pH 8.0 was used for antigen retrieval
    • Immunohistochemical analysis of paraffin-embedded human Malignant melanoma. 1,Tyrosinase Antibody was diluted at 1:200(4°,overnight). 2, EDTA pH 8.0 was used for antigen retrieval