Placental Alkaline Phosphatase(PLAP) (ABT-PLAP) mouse mAb Ready to use

  • Catalog No.:YM6087R
  • Applications:IHC-p
  • Reactivity:Human
    • Gene Name:
    • ALPP PLAP
    • Protein Name:
    • Alkaline phosphatase, placental type (EC 3.1.3.1) (Alkaline phosphatase Regan isozyme) (Placental alkaline phosphatase 1) (PLAP-1)
    • Human Gene Id:
    • 250
    • Human Swiss Prot No:
    • P05187
    • Immunogen:
    • Synthesized peptide derived from human Placental Alkaline Phosphatase(PLAP)
    • Specificity:
    • This antibody detects endogenous levels of human Placental Alkaline Phosphatase(PLAP). Heat-induced epitope retrieval (HIER) Citrate buffer of pH6.0 was highly recommended as antigen repair method in
    • Formulation:
    • Liquid in PBS containing, 0.5% BSA and 0.02% sodium azide.
    • Source:
    • Mouse/IgG1, Kappa
    • Dilution:
    • Ready to use for IHC-p
    • Purification:
    • The antibody was affinity-purified from mouse ascites by affinity-chromatography using specific immunogen.
    • Storage Stability:
    • 4°C/ 1 years
    • Background:
    • alkaline phosphatase, placental(ALPP) Homo sapiens The protein encoded by this gene is an alkaline phosphatase, a metalloenzyme that catalyzes the hydrolysis of phosphoric acid monoesters. It belongs to a multigene family composed of four alkaline phosphatase isoenzymes. The enzyme functions as a homodimer and has a catalytic site containing one magnesium and two zinc ions, which are required for its enzymatic function. The protein is primarily expressed in placental and endometrial tissue; however, strong ectopic expression has been detected in ovarian adenocarcinoma, serous cystadenocarcinoma, and other ovarian cancer cells. [provided by RefSeq, Jan 2015],
    • Function:
    • catalytic activity:A phosphate monoester + H(2)O = an alcohol + phosphate.,cofactor:Binds 1 magnesium ion.,cofactor:Binds 2 zinc ions.,miscellaneous:In most mammals there are four different isozymes: placental, placental-like, intestinal and tissue non-specific (liver/bone/kidney).,online information:Alkaline phosphatase entry,polymorphism:Placental ALP is highly polymorphic, there are at least three common alleles.,similarity:Belongs to the alkaline phosphatase family.,subunit:Homodimer.,
    • Subcellular Location:
    • Cytoplasmic
    • Expression:
    • Cervix,Placenta,