Piperoxan hydrochloride

    • Catalog No.:MC1377
    • Description
    • CasNo:
    • 135-87-5
    • MolecularFormula:
    • C14H20ClNO2
    • Purity:
    • >98%
    • Target:
    • Adrenergic Receptor
    • IC50:
    • adrenoceptor[1]
    • In Vitro:
    • When the medulla is superfused with α2 adrenoceptor antagonist Piperoxane (50 μM; 5 min) while the pons is with artificial cerebrospinal fluid (ACSF), the three inactive preparations display rhythmic phrenic bursts at a low frequency (2-4 c/min), and the phrenic burst frequency of the 12 active ones significantly increases during the last 3 min of Piperoxane applications (163±12% of the previous mean frequency). In active medullary preparations, the effects of NA applications (25 μM; 5 min) are compared when the preparations sre superfused either by ACSF (n=8) or by the α2 adrenoceptor antagonist Piperoxane (50 μM; PIP-ACSF; n=5). NA applications either alone (NA-ACSF) or with Piperoxane (PIP-ACSF+NA) significantly increases the phrenic burst frequency. However, the blockage of the medullary α2 adrenoceptors by Piperoxane potentiates a phrenic burst frequency increase: during the fifth minute of NA applications, the phrenic burst frequency reached 171±11% of the mean control value when
    • Fields:
    • Piperoxan hydrochloride is an α2 adrenoceptor antagonist. adrenoceptor[1]
    • Specificity:
    • Target: Adrenergic Receptor. Fields: Piperoxan hydrochloride is an α2 adrenoceptor antagonist. adrenoceptor[1]
    • Dilution:
    • adrenoceptor[1]
    • Concentration:
    • >98%
    • Storage Stability:
    • 2 years -20°C Powder, 2 weeks4°C in DMSO,6 months-80°C in DMSO
    • MolecularWeight(Da):
    • 269.77
    • Products Images