Amuvatinib (MP-470)

    • Catalog No.:MC0443
      • CasNo:
      • 850879-09-3
      • MolecularFormula:
      • C23H21N5O3S
      • Purity:
      • >98%
      • Target:
      • c-Kit
      • IC50:
      • No data
      • In Vitro:
      • In Vivo:
      • Fields:
      • Amuvatinib (MP-470) is a potent and multi-targeted inhibitor of c-Kit, PDGFRα and Flt3 with IC50 of 10 nM, 40 nM and 81 nM, respectively.
      • Specificity:
      • TargetTargeted inhibitor of c-Kit, PDGFRα and Flt3 with IC50 of 10 nM, 40 nM and 81 nM, respectively.
      • Source:
      • Rabbit
      • Dilution:
      • WB 1:500-2000
      • Concentration:
      • >98%
      • Storage Stability:
      • 2 years -20°C Powder, 2 weeks4°C in DMSO,6 months-80°C in DMSO
      • Other Name:
      • MP-470; MP 470; MP470; HPK 56
      • MolecularWeight(Da):
      • 447.51
      • References:
      • [1]. Bearss DJ, et al. US Patent, US/2008/0226747.[2]. Hurley LH, et al. World Patent, WO/2005/037825.[3]. Mahadevan D, et al. A novel tyrosine kinase switch is a mechanism of imatinib resistance in
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