• Gene Name：
• BTC

• Protein Name：
• Probetacellulin

• Human Gene Id：
• 685

• Human Swiss Prot No：
• P35070

• Mouse Swiss Prot No：
• Q05928

• Specificity：
• Sample Type for Cell Culture Supernates, Cell lysates, Tissue Lysates, Serum, EDTA Plasma, Heparin Plasma

• Storage Stability：
• 2-8°C/6 months

• Other Name：
• BTC;Probetacellulin

• Detection Method：
• Colorimetric

• Background：
• disease:Betacellulin from beta cells could play a role in the vascular complications associated with diabetes.,function:Potent mitogen for retinal pigment epithelial cells and vascular smooth muscle cells. The effects of betacellulin are probably mediated by the EGF receptor and other related receptors.,similarity:Contains 1 EGF-like domain.,subunit:Monomer.,tissue specificity:Synthesized in several tissues and tumor cells. Predominantly expressed in pancreas and small intestine.,

• Function：
• regulation of diuresis, positive regulation of diuresis, regulation of mitosis, regulation of mitotic cell cycle, positive regulation of cell proliferation, regulation of cell cycle process, positive regulation of organelle organization, regulation of cell death, regulation of homeostatic process, regulation of organelle organization, regulation of cell proliferation,regulation of apoptosis, negative regulation of apoptosis, regulation of programmed cell death, negative regulation of programmed cell death, regulation of system process, regulation of excretion, positive regulation of cell differentiation,positive regulation of cell cycle, positive regulation of mitosis, regulation of fibroblast proliferation, positive regulation of fibroblast proliferation, regulation of secretion, positive regulation of secretion, positive regulation of transport,positive regulation of developmental proc

• Subcellular Location：
• [Betacellulin]: Secreted, extracellular space.; [Probetacellulin]: Cell membrane; Single-pass type I membrane protein.

• Expression：
• Synthesized in several tissues and tumor cells. Predominantly expressed in pancreas and small intestine.

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