Phospho Abl1/2 (Y393/439) Cell-Based Colorimetric ELISA Kit
- Catalog No.:KA1008C
- Applications:ELISA
- Reactivity:Human;Mouse
- Gene Name:
- ABL1/ABL2
- Human Swiss Prot No:
- P00519/P42684
- Storage Stability:
- 2-8°C/6 months
- Detection Method:
- Colorimetric
- Function:
- S phase of mitotic cell cycle, regulation of transcription during S-phase of mitotic cell cycle, mitotic cell cycle, DNA metabolic process, DNA repair, mismatch repair, regulation of transcription, DNA-dependent, regulation of transcription from RNA polymerase II promoter, protein amino acid phosphorylation, phosphorus metabolic process, phosphate metabolic process, induction of apoptosis, response to DNA damage stimulus, cytoskeleton organization, cell cycle, cell adhesion, intracellular signaling cascade, induction of apoptosis by intracellular signals, DNA damage response, signal transduction resulting in induction of apoptosis, regulation of cell death, positive regulation of cell death, induction of programmed cell death, phosphorylation, peptidyl-tyrosine phosphorylation, peptidyl-tyrosine modification, cell cycle process, cell cycle phase, biological adhesion, actin filament-based
- Subcellular Location:
- Cytoplasm, cytoskeleton. Nucleus. Mitochondrion . Shuttles between the nucleus and cytoplasm depending on environmental signals. Sequestered into the cytoplasm through interaction with 14-3-3 proteins. Localizes to mitochondria in response to oxidative stress (By similarity). .; [Isoform IB]: Nucleus membrane; Lipid-anchor. The myristoylated c-ABL protein is reported to be nuclear.
- Expression:
- Widely expressed.
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