IL-1 Receptor 1 Polyclonal Antibody

    • 货号:YT6285
    • 应用:WB, ELISA
    • 种属:Human
      • 基因名称:
      • IL1R1 IL1R IL1RA IL1RT1
      • 蛋白名称:
      • IL-1 Receptor 1
      • Human Gene Id:
      • 3554
      • Human Swiss Prot No:
      • P14778
      • 免疫原:
      • Synthesized peptide derived from human IL-1 Receptor 1
      • 特异性:
      • This antibody detects endogenous levels of human IL-1 Receptor 1
      • 组成:
      • Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
      • 来源:
      • Rabbit
      • 稀释:
      • WB 1:500-2000, ELISA(peptide)1:5000-20000
      • 纯化工艺:
      • The antibody was affinity-purified from mouse ascites by affinity-chromatography using specific immunogen.
      • 浓度:
      • 1 mg/ml
      • 储存:
      • -20°C/1 year
      • 其他名称:
      • Interleukin-1 receptor type 1 (IL-1R-1) (IL-1RT-1) (IL-1RT1) (CD121 antigen-like family member A) (Interleukin-1 receptor alpha) (IL-1R-alpha) (Interleukin-1 receptor type I) (p80) (CD antigen CD121a) [Cleaved into: Interleukin-1 receptor type 1, membrane form (mIL-1R1) (mIL-1RI); Interleukin-1 receptor type 1, soluble form (sIL-1R1) (sIL-1RI)]
      • 实测条带:
      • 65
      • 背景:
      • interleukin 1 receptor type 1(IL1R1) Homo sapiens This gene encodes a cytokine receptor that belongs to the interleukin-1 receptor family. The encoded protein is a receptor for interleukin-1 alpha, interleukin-1 beta, and interleukin-1 receptor antagonist. It is an important mediator involved in many cytokine-induced immune and inflammatory responses. This gene is located in a cluster of related cytokine receptor genes on chromosome 2q12. [provided by RefSeq, Dec 2013],
      • 功能:
      • function:Receptor for interleukin-1 alpha (IL-1A), beta (IL-1B), and interleukin-1 receptor antagonist protein (IL-1RA). Binding to the agonist leads to the activation of NF-kappa-B. Signaling involves formation of a ternary complex containing IL1RAP, TOLLIP, MYD88, and IRAK1 or IRAK2.,similarity:Belongs to the interleukin-1 receptor family.,similarity:Contains 1 TIR domain.,similarity:Contains 3 Ig-like C2-type (immunoglobulin-like) domains.,subunit:Binds IL1RAP.,
      • 细胞定位:
      • extracellular region,plasma membrane,integral component of plasma membrane,cell surface,membrane,integral component of membrane,
      • 组织表达:
      • Brain,Epithelium,Liver,PCR rescued clones,Placenta,T-cell,
      • 产品图片
      • Western blot analysis of various lysates, primary antibody was diluted at 1:1000, 4° over night, secondary antibody(cat: RS23920)was diluted at 1:10000, 37° 1hour.