• 靶点：
• Ox40L

• 简介：
• >>Cytokine-cytokine receptor interaction

• 基因名称：
• TNFSF4

• 蛋白名称：
• Tumor necrosis factor ligand superfamily member 4

• Human Gene Id：
• 7292

• Human Swiss Prot No：
• P23510

• Mouse Gene Id：
• 22164

• Mouse Swiss Prot No：
• P43488

• Rat Gene Id：
• 89814

• Rat Swiss Prot No：
• Q9Z2P3

• 免疫原：
• The antiserum was produced against synthesized peptide derived from the Internal region of human TNFSF4. AA range:31-80

• 特异性：
• Ox40L Polyclonal Antibody detects endogenous levels of Ox40L protein.

• 组成：
• Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

• 来源：
• Polyclonal, Rabbit,IgG

• 稀释：
• WB 1:500 - 1:2000. IHC: 1:100-1:300. IF 1:100-1:300. ELISA: 1:10000. Not yet tested in other applications.

• 纯化工艺：
• The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

• 浓度：
• 1 mg/ml

• 储存：
• -15°C to -25°C/1 year(Do not lower than -25°C)

• 其他名称：
• TNFSF4;TXGP1;Tumor necrosis factor ligand superfamily member 4;Glycoprotein Gp34;OX40 ligand;OX40L;TAX transcriptionally-activated glycoprotein 1;CD252

• 实测条带：
• 21kD

• 背景：
• This gene encodes a cytokine of the tumor necrosis factor (TNF) ligand family. The encoded protein functions in T cell antigen-presenting cell (APC) interactions and mediates adhesion of activated T cells to endothelial cells. Polymorphisms in this gene have been associated with Sjogren's syndrome and systemic lupus erythematosus. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2014],

• 功能：
• disease:Genetic variation in TNFSF4 influences susceptibility to systemic lupus erythematosus (SLE) [MIM:152700]. SLE is a chronic, inflammatory and often febrile multisystemic disorder of connective tissue. It affects principally the skin, joints, kidneys and serosal membranes. It is thought to represent a failure of the regulatory mechanisms of the autoimmune system.,function:Cytokine that binds to TNFRSF4. Co-stimulates T-cell proliferation and cytokine production.,induction:By human T-cell leukemia virus type I transactivator P40-TAX.,similarity:Belongs to the tumor necrosis factor family.,subunit:Homotrimer.,

• 细胞定位：
• Membrane; Single-pass type II membrane protein.

• 组织表达：
• Testis,

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