Wee 2 Polyclonal Antibody

    • 货号:YT4904
    • 应用:WB;ELISA
    • 种属:Human;Rat;Mouse;
      • 靶点:
      • Wee 2
      • 简介:
      • >>Cell cycle;>>Human immunodeficiency virus 1 infection
      • 基因名称:
      • WEE2
      • 蛋白名称:
      • Wee1-like protein kinase 2
      • Human Swiss Prot No:
      • P0C1S8
      • Mouse Swiss Prot No:
      • Q66JT0
      • 免疫原:
      • The antiserum was produced against synthesized peptide derived from human WEE2. AA range:151-200
      • 特异性:
      • Wee 2 Polyclonal Antibody detects endogenous levels of Wee 2 protein.
      • 组成:
      • Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
      • 来源:
      • Polyclonal, Rabbit,IgG
      • 稀释:
      • WB 1:500 - 1:2000. ELISA: 1:5000. Not yet tested in other applications.
      • 纯化工艺:
      • The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
      • 浓度:
      • 1 mg/ml
      • 储存:
      • -15°C to -25°C/1 year(Do not lower than -25°C)
      • 其他名称:
      • WEE2;WEE1B;Wee1-like protein kinase 2;Wee1-like protein kinase 1B;Wee1B kinase
      • 实测条带:
      • 60kD
      • 背景:
      • catalytic activity:ATP + a [protein]-L-tyrosine = ADP + a [protein]-L-tyrosine phosphate.,function:Phosphorylates and inhibits CDC2. May act as a negative regulator of entry into mitosis (G2 to M transition).,PTM:Phosphorylated .,similarity:Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. WEE1 subfamily.,similarity:Contains 1 protein kinase domain.,tissue specificity:Expressed in testis.,
      • 功能:
      • catalytic activity:ATP + a [protein]-L-tyrosine = ADP + a [protein]-L-tyrosine phosphate.,function:Phosphorylates and inhibits CDC2. May act as a negative regulator of entry into mitosis (G2 to M transition).,PTM:Phosphorylated .,similarity:Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. WEE1 subfamily.,similarity:Contains 1 protein kinase domain.,tissue specificity:Expressed in testis.,
      • 细胞定位:
      • Nucleus .
      • 组织表达:
      • Expressed in oocytes (at protein level) (PubMed:29606300). May also be expressed in testis (PubMed:11029659).
      • 产品图片
      • Western blot analysis of lysates from HUVEC cells, using WEE2 Antibody. The lane on the right is blocked with the synthesized peptide.
      • Western blot analysis of the lysates from K562 cells using WEE2 antibody.