Txk Polyclonal Antibody

    • 货号:YT4790
    • 应用:IHC;IF;ELISA
    • 种属:Human;Rat;Mouse;
      • 靶点:
      • Txk
      • 简介:
      • >>Leukocyte transendothelial migration
      • 基因名称:
      • TXK
      • 蛋白名称:
      • Tyrosine-protein kinase TXK
      • Human Gene Id:
      • 7294
      • Human Swiss Prot No:
      • P42681
      • Mouse Swiss Prot No:
      • P42682
      • 免疫原:
      • Synthesized peptide derived from the Internal region of human Txk.
      • 特异性:
      • Txk Polyclonal Antibody detects endogenous levels of Txk protein.
      • 组成:
      • Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
      • 来源:
      • Polyclonal, Rabbit,IgG
      • 稀释:
      • IHC 1:100 - 1:300. ELISA: 1:40000.. IF 1:50-200
      • 纯化工艺:
      • The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
      • 浓度:
      • 1 mg/ml
      • 储存:
      • -15°C to -25°C/1 year(Do not lower than -25°C)
      • 其他名称:
      • TXK;PTK4;RLK;Tyrosine-protein kinase TXK;Protein-tyrosine kinase 4;Resting lymphocyte kinase
      • 分子量:
      • 61kD
      • 背景:
      • catalytic activity:ATP + a [protein]-L-tyrosine = ADP + a [protein]-L-tyrosine phosphate.,similarity:Belongs to the protein kinase superfamily. Tyr protein kinase family. TEC subfamily.,similarity:Contains 1 protein kinase domain.,similarity:Contains 1 SH2 domain.,similarity:Contains 1 SH3 domain.,tissue specificity:Expressed in T-cells and some myeloid cell lines.,
      • 功能:
      • catalytic activity:ATP + a [protein]-L-tyrosine = ADP + a [protein]-L-tyrosine phosphate.,similarity:Belongs to the protein kinase superfamily. Tyr protein kinase family. TEC subfamily.,similarity:Contains 1 protein kinase domain.,similarity:Contains 1 SH2 domain.,similarity:Contains 1 SH3 domain.,tissue specificity:Expressed in T-cells and some myeloid cell lines.,
      • 细胞定位:
      • Cytoplasm . Nucleus . Cell membrane ; Peripheral membrane protein . Localizes in the vicinity of cell surface receptors in the plasma membrane after receptor stimulation. Translocates into the nucleus and enhances IFN-gamma gene transcription in T-cells.
      • 组织表达:
      • Expressed in T-cells and some myeloid cell lines. Expressed in Th1/Th0 cells with IFN-gamma-producing potential.
      • 产品图片
      • Immunohistochemical analysis of paraffin-embedded human oophoroma. 1, Antibody was diluted at 1:200(4° overnight). 2, Tris-EDTA,pH9.0 was used for antigen retrieval. 3,Secondary antibody was diluted at 1:200(room temperature, 45min).