• 靶点：
• TASK-5

• 基因名称：
• KCNK15

• 蛋白名称：
• Potassium channel subfamily K member 15

• Human Gene Id：
• 60598

• Human Swiss Prot No：
• Q9H427

• 免疫原：
• The antiserum was produced against synthesized peptide derived from human KCNK15. AA range:273-322

• 特异性：
• TASK-5 Polyclonal Antibody detects endogenous levels of TASK-5 protein.

• 组成：
• Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

• 来源：
• Polyclonal, Rabbit,IgG

• 稀释：
• WB 1:500 - 1:2000. IHC 1:100 - 1:300. ELISA: 1:20000.. IF 1:50-200

• 纯化工艺：
• The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

• 浓度：
• 1 mg/ml

• 储存：
• -15°C to -25°C/1 year(Do not lower than -25°C)

• 其他名称：
• KCNK15;TASK5;Potassium channel subfamily K member 15;Acid-sensitive potassium channel protein TASK-5;TWIK-related acid-sensitive K(+) channel 5;Two pore potassium channel KT3.3;Two pore K(+) channel KT3.3

• 实测条带：
• 42kD

• 背景：
• potassium two pore domain channel subfamily K member 15(KCNK15) Homo sapiens This gene encodes one of the members of the superfamily of potassium channel proteins containing two pore-forming P domains. The product of this gene has not been shown to be a functional channel, however, it may require other non-pore-forming proteins for activity. [provided by RefSeq, Jul 2008],

• 功能：
• function:Probable potassium channel subunit. No channel activity observed in heterologous systems. May need to associate with another protein to form a functional channel.,polymorphism:Three variant polypeptides are known: TASK-5A, TASK-5B and TASK-5C. The sequence shown is that of TASK-5C.,similarity:Belongs to the two pore domain potassium channel (TC 1.A.1.8) family.,subunit:Heterodimer .,tissue specificity:Detected in pancreas, heart, placenta, lung, liver, kidney, ovary, testis, skeletal muscle and adrenal gland, and at lower levels in prostate, spleen and thyroid gland.,

• 细胞定位：
• Membrane; Multi-pass membrane protein.

• 组织表达：
• Detected in pancreas, heart, placenta, lung, liver, kidney, ovary, testis, skeletal muscle and adrenal gland, and at lower levels in prostate, spleen and thyroid gland.

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