NCKX3 Polyclonal Antibody
- 货号：YT2993
- 应用：WB;ELISA
- 种属：Human;Mouse;Rat
- 蛋白名称：
- Sodium/potassium/calcium exchanger 3
- 免疫原：
- The antiserum was produced against synthesized peptide derived from human SLC24A3. AA range:354-403
- 特异性：
- NCKX3 Polyclonal Antibody detects endogenous levels of NCKX3 protein.
- 组成：
- Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
- 来源：
- Polyclonal, Rabbit,IgG
- 稀释：
- WB 1:500 - 1:2000. ELISA: 1:20000. Not yet tested in other applications.
- 纯化工艺：
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
- 储存：
- -15°C to -25°C/1 year(Do not lower than -25°C)
- 其他名称：
- SLC24A3;NCKX3;Sodium/potassium/calcium exchanger 3;Na(+)/K(+)/Ca(2+)-exchange protein 3;Solute carrier family 24 member 3
- 背景：
- Plasma membrane sodium/calcium exchangers are an important component of intracellular calcium homeostasis and electrical conduction. Potassium-dependent sodium/calcium exchangers such as SLC24A3 are believed to transport 1 intracellular calcium and 1 potassium ion in exchange for 4 extracellular sodium ions (Kraev et al., 2001 [PubMed 11294880]).[supplied by OMIM, Mar 2008],
- 功能：
- function:Transports 1 Ca(2+) and 1 K(+) in exchange for 4 Na(+).,similarity:Belongs to the sodium/potassium/calcium exchanger family. SLC24A subfamily.,tissue specificity:Abundant in the brain. Expressed at low levels in the aorta, uterus and intestine.,
- 细胞定位：
- Cell membrane ; Multi-pass membrane protein .
- 组织表达：
- Abundant in the brain (PubMed:11294880). Expressed at low levels in the aorta, uterus and intestine (PubMed:11294880).
- Western blot analysis of SLC24A3 Antibody. The lane on the right is blocked with the SLC24A3 peptide.
- Western blot analysis of the lysates from K562 cells using SLC24A3 antibody.
