GABA T-3 Polyclonal Antibody
- 货号：YT1820
- 应用：WB;ELISA
- 种属：Human;Mouse;Rat
- 简介：
- >>Synaptic vesicle cycle;>>GABAergic synapse
- 蛋白名称：
- Sodium- and chloride-dependent GABA transporter 3
- 免疫原：
- Synthesized peptide derived from GABA T-3 . at AA range: 370-450
- 特异性：
- GABA T-3 Polyclonal Antibody detects endogenous levels of GABA T-3 protein.
- 组成：
- Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
- 来源：
- Polyclonal, Rabbit,IgG
- 稀释：
- WB 1:500 - 1:2000. ELISA: 1:10000. Not yet tested in other applications.
- 纯化工艺：
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
- 储存：
- -15°C to -25°C/1 year(Do not lower than -25°C)
- 其他名称：
- SLC6A11;GABT3;GAT3;Sodium- and chloride-dependent GABA transporter 3;GAT-3;Solute carrier family 6 member 11
- 背景：
- The protein encoded by this gene is a sodium-dependent transporter that uptakes gamma-aminobutyric acid (GABA), an inhibitory neurotransmitter, which ends the GABA neurotransmission. Defects in this gene may result in epilepsy, behavioral problems, or intellectual problems. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Dec 2015],
- 功能：
- function:Terminates the action of GABA by its high affinity sodium-dependent reuptake into presynaptic terminals.,similarity:Belongs to the sodium:neurotransmitter symporter (SNF) family.,tissue specificity:Widespread distribution in the brain.,
- 细胞定位：
- Membrane; Multi-pass membrane protein.
- 组织表达：
- Widespread distribution in the brain.
