- 靶点：
- GABA T-1
- 简介：
- >>Synaptic vesicle cycle;>>GABAergic synapse
- 基因名称：
- SLC6A1
- 蛋白名称：
- Sodium- and chloride-dependent GABA transporter 1
- Human Gene Id：
- 6529
- Human Swiss Prot No：
- P30531
- Mouse Gene Id：
- 232333
- Mouse Swiss Prot No：
- P31648
- Rat Gene Id：
- 79212
- Rat Swiss Prot No：
- P23978
- 免疫原：
- The antiserum was produced against synthesized peptide derived from human SLC6A1. AA range:381-430
- 特异性：
- GABA T-1 Polyclonal Antibody detects endogenous levels of GABA T-1 protein.
- 组成：
- Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
- 来源：
- Polyclonal, Rabbit,IgG
- 稀释：
- WB 1:500 - 1:2000. ELISA: 1:40000. Not yet tested in other applications.
- 纯化工艺：
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
- 浓度：
- 1 mg/ml
- 储存：
- -15°C to -25°C/1 year(Do not lower than -25°C)
- 其他名称：
- SLC6A1;GABATR;GABT1;GAT1;Sodium- and chloride-dependent GABA transporter 1;GAT-1;Solute carrier family 6 member 1
- 实测条带：
- 67kD
- 背景：
- The SLC6A1 gene encodes a gamma-aminobutyric acid (GABA) transporter, which removes GABA from the synaptic cleft (Hirunsatit et al., 2009 [PubMed 19077666]).[supplied by OMIM, Jul 2009],
- 功能：
- domain:The PDZ domain-binding motif is involved in the interaction with MPP5.,function:Terminates the action of GABA by its high affinity sodium-dependent reuptake into presynaptic terminals.,miscellaneous:This protein is the target of psychomotor stimulants such as amphetamines or cocaine.,similarity:Belongs to the sodium:neurotransmitter symporter (SNF) family.,subcellular location:Localized at the plasma membrane and in a subset of intracellular vesicles. Localized at the presynaptic terminals of interneurons.,subunit:Interacts with MPP5.,
- 细胞定位：
- Cell membrane; Multi-pass membrane protein. Membrane; Multi-pass membrane protein. Cell junction, synapse, presynapse . Localized at the plasma membrane and in a subset of intracellular vesicles. Localized at the presynaptic terminals of interneurons (By similarity). .
- 组织表达：
- Brain,
The effect of modified Qiyuan paste on mice with low immunity and sleep deprivation by regulating GABA nerve and immune system Chinese Medicine Rong Mei WB Mouse brain tissue
货号：YT1819
- June 19-2018
- WESTERN IMMUNOBLOTTING PROTOCOL
- June 19-2018
- IMMUNOHISTOCHEMISTRY-PARAFFIN PROTOCOL
- June 19-2018
- IMMUNOFLUORESCENCE PROTOCOL
- September 08-2020
- FLOW-CYTOMEYRT-PROTOCOL
- May 20-2022
- Cell-Based ELISA│解您多样本WB检测之困扰
- July 13-2018
- CELL-BASED-ELISA-PROTOCOL-FOR-ACETYL-PROTEIN
- July 13-2018
- CELL-BASED-ELISA-PROTOCOL-FOR-PHOSPHO-PROTEIN
- July 13-2018
- Antibody-FAQs
- 产品图片
- Western blot analysis of SLC6A1 Antibody. The lane on the right is blocked with the SLC6A1 peptide.
- Western blot analysis of the lysates from HeLa cells using SLC6A1 antibody.
