Cdk10 Polyclonal Antibody

    • 货号:YT0830
    • 应用:WB;IHC;IF;ELISA
    • 种属:Human;Mouse;Rat
      • 靶点:
      • Cdk10
      • 基因名称:
      • CDK10
      • 蛋白名称:
      • Cyclin-dependent kinase 10
      • Human Gene Id:
      • 8558
      • Human Swiss Prot No:
      • Q15131
      • Mouse Swiss Prot No:
      • Q3UMM4
      • 免疫原:
      • The antiserum was produced against synthesized peptide derived from human CDK10. AA range:51-100
      • 特异性:
      • Cdk10 Polyclonal Antibody detects endogenous levels of Cdk10 protein.
      • 组成:
      • Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
      • 来源:
      • Polyclonal, Rabbit,IgG
      • 稀释:
      • WB 1:500 - 1:2000. IHC 1:100 - 1:300. ELISA: 1:10000.. IF 1:50-200
      • 纯化工艺:
      • The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
      • 浓度:
      • 1 mg/ml
      • 储存:
      • -15°C to -25°C/1 year(Do not lower than -25°C)
      • 其他名称:
      • CDK10;Cyclin-dependent kinase 10;Cell division protein kinase 10;Serine/threonine-protein kinase PISSLRE
      • 实测条带:
      • 43kD
      • 背景:
      • The protein encoded by this gene belongs to the CDK subfamily of the Ser/Thr protein kinase family. The CDK subfamily members are highly similar to the gene products of S. cerevisiae cdc28, and S. pombe cdc2, and are known to be essential for cell cycle progression. This kinase has been shown to play a role in cellular proliferation and its function is limited to cell cycle G2-M phase. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, May 2009],
      • 功能:
      • catalytic activity:ATP + a protein = ADP + a phosphoprotein.,similarity:Belongs to the protein kinase superfamily.,similarity:Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. CDC2/CDKX subfamily.,similarity:Contains 1 protein kinase domain.,
      • 细胞定位:
      • Cytoplasm, cytoskeleton, cilium basal body .
      • 组织表达:
      • Brain,Colon,Kidney,Lung,
      • 产品图片
      • Western Blot analysis of various cells using Cdk10 Polyclonal Antibody diluted at 1:500
      • Western Blot analysis of 293 cells using Cdk10 Polyclonal Antibody diluted at 1:500
      • Western blot analysis of lysates from 293 cells, using CDK10 Antibody. The lane on the right is blocked with the synthesized peptide.
      • Immunohistochemical analysis of paraffin-embedded human Colon cancer. 1, Antibody was diluted at 1:200(4° overnight). 2, Tris-EDTA,pH9.0 was used for antigen retrieval. 3,Secondary antibody was diluted at 1:200(room temperature, 45min).