• 靶点：
• Bub3

• 简介：
• >>Cell cycle;>>Human T-cell leukemia virus 1 infection

• 基因名称：
• BUB3

• 蛋白名称：
• Mitotic checkpoint protein BUB3

• Human Gene Id：
• 9184

• Human Swiss Prot No：
• O43684

• Mouse Gene Id：
• 12237

• Mouse Swiss Prot No：
• Q9WVA3

• 免疫原：
• The antiserum was produced against synthesized peptide derived from human BUB3. AA range:279-328

• 特异性：
• Bub3 Polyclonal Antibody detects endogenous levels of Bub3 protein.

• 组成：
• Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

• 来源：
• Polyclonal, Rabbit,IgG

• 稀释：
• WB 1:500 - 1:2000. IHC 1:100 - 1:300. IF 1:200 - 1:1000. ELISA: 1:5000. Not yet tested in other applications.

• 纯化工艺：
• The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

• 浓度：
• 1 mg/ml

• 储存：
• -15°C to -25°C/1 year(Do not lower than -25°C)

• 其他名称：
• BUB3;Mitotic checkpoint protein BUB3

• 实测条带：
• 40kD

• 背景：
• This gene encodes a protein involved in spindle checkpoint function. The encoded protein contains four WD repeat domains and has sequence similarity with the yeast BUB3 protein. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. [provided by RefSeq, Jul 2008],

• 功能：
• function:Required for kinetochore localization of BUB1.,similarity:Belongs to the WD repeat BUB3 family.,similarity:Contains 5 WD repeats.,subunit:Interacts with BUB1 and BUBR1.,

• 细胞定位：
• Nucleus. Chromosome, centromere, kinetochore . Starts to localize at kinetochores in prometaphase I (Pro-MI) stage and maintains the localization until the metaphase I-anaphase I (MI-AI) transition. .

• 组织表达：
• Brain,Epithelium,Placenta,Spleen,Testis,

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