- 靶点:
- TH
- 基因名称:
- TH
- 蛋白名称:
- Tyrosine 3-monooxygenase
- Human Swiss Prot No:
- P07101
- Rat Gene Id:
- 25085
- Rat Swiss Prot No:
- P04177
- 免疫原:
- The antiserum was produced against synthesized peptide derived from mouse Tyrosine Hydroxylase around the phosphorylation site of Ser8. AA range:2-51
- 特异性:
- Phospho-TH (S8) Polyclonal Antibody detects endogenous levels of TH protein only when phosphorylated at S8.
- 组成:
- Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
- 来源:
- Polyclonal, Rabbit,IgG
- 稀释:
- WB 1:500 - 1:2000. IHC 1:100 - 1:300. ELISA: 1:5000.. IF 1:50-200
- 纯化工艺:
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
- 浓度:
- 1 mg/ml
- 储存:
- -15°C to -25°C/1 year(Do not lower than -25°C)
- 其他名称:
- TH;TYH;Tyrosine 3-monooxygenase;Tyrosine 3-hydroxylase;TH
- 实测条带:
- 62kD
- 背景:
- The tyrosine hydroxylase encoded by TH is involved in the conversion of tyrosine to dopamine. It is the rate-limiting enzyme in the synthesis of catecholamines, hence plays a key role in the physiology of adrenergic neurons. Mutations in this gene have been associated with autosomal recessive Segawa syndrome. Alternatively spliced transcript variants encoding different isoforms have been noted for this gene.
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- 产品图片
- Western blot analysis of 293T 3T3 lysis using Phospho-TH (S8) antibody. Antibody was diluted at 1:1000
- Immunohistochemistry analysis of paraffin-embedded human brain, using Tyrosine Hydroxylase (Phospho-Ser8) Antibody. The picture on the right is blocked with the phospho peptide.
- Western blot analysis of lysates from HepG2 cells treated with Anisomycin 25ug/ml 30', using Tyrosine Hydroxylase (Phospho-Ser8) Antibody. The lane on the right is blocked with the phospho peptide.