• 靶点：
• CDX2

• 简介：
• >>Gastric cancer

• 基因名称：
• CDX2

• 蛋白名称：
• Homeobox protein CDX-2

• Human Gene Id：
• 1045

• Human Swiss Prot No：
• Q99626

• Mouse Gene Id：
• 12591

• Mouse Swiss Prot No：
• P43241

• 免疫原：
• Synthetic Peptide of CDX2

• 特异性：
• The antibody detects endogenous CDX2 proteins.

• 组成：
• PBS, pH 7.4, containing 0.5%BSA, 0.02% sodium azide as Preservative and 50% Glycerol.

• 来源：
• Monoclonal, Mouse

• 稀释：
• WB 1:1000 IHC 1:200 IF 1:200

• 纯化工艺：
• The antibody was affinity-purified from mouse ascites by affinity-chromatography using specific immunogen.

• 储存：
• -15°C to -25°C/1 year(Do not lower than -25°C)

• 其他名称：
• CDX2;CDX3;Homeobox protein CDX-2;CDX-3;Caudal-type homeobox protein 2

• 实测条带：
• 42kD

• 背景：
• This gene is a member of the caudal-related homeobox transcription factor gene family. The encoded protein is a major regulator of intestine-specific genes involved in cell growth an differentiation. This protein also plays a role in early embryonic development of the intestinal tract. Aberrant expression of this gene is associated with intestinal inflammation and tumorigenesis. [provided by RefSeq, Jan 2012],

• 功能：
• function:Involved in the transciptional regulation of multiple genes expressed in the intestinal epithelium. Important in broad range of functions from early differentiation to maintenance of the intestinal epithelial lining of both the small and large intestine.,PTM:Phosphorylation of Ser-60 mediates the transactivation capacity.,similarity:Belongs to the Caudal homeobox family.,similarity:Contains 1 homeobox DNA-binding domain.,

• 细胞定位：
• Nucleus .

• 组织表达：
• Detected in small intestine, colon and pancreas.

Alpha lipoamide inhibits diabetic kidney fibrosis via improving mitochondrial function and regulating RXRα expression and activation
货号：YM3057

The role of CDX2 in renal tubular lesions during diabetic kidney disease. Aging-US Aging-Us. 2021 Mar 15; 13(5): 6782–6803 IHC Mouse,Human Kidney
货号：YM3057

Helicobacter pylori promotes gastric intestinal metaplasia through activation of IRF3-mediated kynurenine pathway. Wanfu Xu IF,IHC Mouse 1:800 gastric mucosa tissue
货号：YM3057

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