Recombinant Human CD340 protein ,C- His Tag
- 纯度：
- >90% as determined by SDS-PAGE
- 体内研究：
- < 1.0 EU per μg of the protein as determined by the LAL method.
- 序列：
- A DNA sequence encoding the human ERBB2(Met1-Thr652) was fused with the C-terminal His Tag
- 组成：
- Supplied as solution form in PBS pH 7.5./ Lyophilized from PBS pH 7.5.
- 稀释：
- Reconstitute in sterile water for a stock solution
- 浓度：
- >90% as determined by SDS-PAGE
- 储存：
- Use a manual defrost freezer and avoid repeated freeze thaw cycles.
Store at 2 to 8 °C for one week .
Store at -20 to -80 °C for twelve months from the date of receipt.
- 其他名称：
- HER-2,HER-2/neu,HER2,MLN 19,MLN19,NEU,NGL,TKR1
- 细胞定位：
- [Isoform 1]: Cell membrane ; Single-pass type I membrane protein. Early endosome . Cytoplasm, perinuclear region. Nucleus. Translocation to the nucleus requires endocytosis, probably endosomal sorting and is mediated by importin beta-1/KPNB1. Also detected in VPS35-positive endosome-to-TGN retrograde vesicles (PubMed:31138794). .; [Isoform 2]: Cytoplasm. Nucleus.; [Isoform 3]: Cytoplasm. Nucleus.
- 组织表达：
- Expressed in a variety of tumor tissues including primary breast tumors and tumors from small bowel, esophagus, kidney and mouth.
