Phospho PLCG2 (Y753) Cell-Based Colorimetric ELISA Kit
- 货号：KA1215C
- 应用：ELISA
- 种属：Human;Mouse;Rat
- 基因名称：
- PLCG2
- Human Gene Id：
- 5336
- Human Swiss Prot No：
- P16885
- Mouse Swiss Prot No：
- Q8CIH5
- Rat Swiss Prot No：
- P24135
- 储存：
- 2-8°C/6 months
- 其他名称：
- 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-2 (EC 3.1.4.11) (Phosphoinositide phospholipase C-gamma-2) (Phospholipase C-IV) (PLC-IV) (Phospholipase C-gamma-2) (PLC-gamma-2)
- 检测方法：
- Colorimetric
- 背景：
- catalytic activity:1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate + H(2)O = 1D-myo-inositol 1,4,5-trisphosphate + diacylglycerol.,cofactor:Calcium.,function:The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. It is a crucial enzyme in transmembrane signaling.,PTM:Phosphorylated on tyrosine residues; upon ligand-induced activation of a variety of growth factor receptors and immune system receptors. Increases phospholipase activity.,similarity:Contains 1 C2 domain.,similarity:Contains 1 PH domain.,similarity:Contains 1 PI-PLC X-box domain.,similarity:Contains 1 PI-PLC Y-box domain.,similarity:Contains 1 SH3 domain.,similarity:Contains 2 SH2 domains.,
- 功能：
- cell activation, response to molecule of bacterial origin, activation of immune response, cell activation during immune response, lymphocyte activation during immune response, B cell activation during immune response, mature B cell differentiation during immune response, follicular B cell differentiation, mature B cell differentiation, leukocyte activation during immune response, immune response-activating cell surface receptor signaling pathway, immune system development, leukocyte differentiation, positive regulation of immune system process, immune response-activating signal transduction, immune response-regulating signal transduction, immune response-regulating cell surface receptor signaling pathway, inositol metabolic process, inositol biosynthetic process, phospholipid metabolic process, cellular ion homeostasis, cellular calcium ion homeostasis, cellular metal ion homeostasis, im
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