KKIAMRE Polyclonal Antibody
- Catalog No.:YT2482
- Applications:WB;IHC;IF;ELISA
- Reactivity:Human;Rat;Mouse;
- Target:
- KKIAMRE
- Gene Name:
- CDKL2
- Protein Name:
- Cyclin-dependent kinase-like 2
- Human Gene Id:
- 8999
- Human Swiss Prot No:
- Q92772
- Mouse Swiss Prot No:
- Q9QUK0
- Immunogen:
- The antiserum was produced against synthesized peptide derived from human CDKL2. AA range:211-260
- Specificity:
- KKIAMRE Polyclonal Antibody detects endogenous levels of KKIAMRE protein.
- Formulation:
- Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
- Source:
- Polyclonal, Rabbit,IgG
- Dilution:
- WB 1:500 - 1:2000. IHC 1:100 - 1:300. ELISA: 1:10000.. IF 1:50-200
- Purification:
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
- Concentration:
- 1 mg/ml
- Storage Stability:
- -15°C to -25°C/1 year(Do not lower than -25°C)
- Other Name:
- CDKL2;Cyclin-dependent kinase-like 2;Protein kinase p56 KKIAMRE;Serine/threonine-protein kinase KKIAMRE
- Observed Band(KD):
- 56kD
- Background:
- This gene product is a member of a large family of CDC2-related serine/threonine protein kinases. It accumulates primarily in the cytoplasm, with lower levels in the nucleus. [provided by RefSeq, Jul 2008],
- Function:
- catalytic activity:ATP + a protein = ADP + a phosphoprotein.,domain:The [NKR]KIAxRE motif seems to be a cyclin-binding region.,similarity:Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. CDC2/CDKX subfamily.,similarity:Contains 1 protein kinase domain.,tissue specificity:Expressed in testis and kidney, and at lower level in brain and lung.,
- Subcellular Location:
- Cytoplasm . Nucleus .
- Expression:
- Expressed in testis and kidney, and at lower level in brain and lung.
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- Antibody-FAQs
- Products Images
- Western blot analysis of lysates from Jurkat and 293 cells, using CDKL2 Antibody. The lane on the right is blocked with the synthesized peptide.
- Immunohistochemical analysis of paraffin-embedded human Breast cancer. 1, Antibody was diluted at 1:200(4° overnight). 2, Tris-EDTA,pH9.0 was used for antigen retrieval. 3,Secondary antibody was diluted at 1:200(room temperature, 45min).