KKIALRE Polyclonal Antibody
- Catalog No.:YT2481
- Applications:WB;IHC;IF;ELISA
- Reactivity:Human;Rat
- Target:
- KKIALRE
- Gene Name:
- CDKL1
- Protein Name:
- Cyclin-dependent kinase-like 1
- Human Gene Id:
- 8814
- Human Swiss Prot No:
- Q00532
- Mouse Swiss Prot No:
- Q8CEQ0
- Rat Gene Id:
- 314198
- Rat Swiss Prot No:
- Q66HE7
- Immunogen:
- The antiserum was produced against synthesized peptide derived from human CDKL1. AA range:281-330
- Specificity:
- KKIALRE Polyclonal Antibody detects endogenous levels of KKIALRE protein.
- Formulation:
- Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
- Source:
- Polyclonal, Rabbit,IgG
- Dilution:
- WB 1:500 - 1:2000. IHC 1:100 - 1:300. ELISA: 1:10000.. IF 1:50-200
- Purification:
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
- Concentration:
- 1 mg/ml
- Storage Stability:
- -15°C to -25°C/1 year(Do not lower than -25°C)
- Other Name:
- CDKL1;Cyclin-dependent kinase-like 1;Protein kinase p42 KKIALRE;Serine/threonine-protein kinase KKIALRE
- Observed Band(KD):
- 42kD
- Background:
- This gene product is a member of a large family of CDC2-related serine/threonine protein kinases. It accumulates primarily in the nucleus. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Aug 2013],
- Function:
- catalytic activity:ATP + a protein = ADP + a phosphoprotein.,domain:The [NKR]KIAxRE motif seems to be a cyclin-binding region.,similarity:Belongs to the protein kinase superfamily.,similarity:Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. CDC2/CDKX subfamily.,similarity:Contains 1 protein kinase domain.,tissue specificity:Highly expressed in kidney, and to a lower extent in ovary.,
- Subcellular Location:
- Cytoplasm . Nucleus .
- Expression:
- Highly expressed in kidney, and to a lower extent in ovary.
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- Antibody-FAQs
- Products Images
- Western Blot analysis of various cells using KKIALRE Polyclonal Antibody diluted at 1:500
- Immunohistochemical analysis of paraffin-embedded Human brain. Antibody was diluted at 1:100(4° overnight). High-pressure and temperature Tris-EDTA,pH8.0 was used for antigen retrieval. Negetive contrl (right) obtaned from antibody was pre-absorbed by immunogen peptide.
- Western blot analysis of lysates from COLO205 cells, using CDKL1 Antibody. The lane on the right is blocked with the synthesized peptide.
- Western blot analysis of the lysates from COLO205 cells using CDKL1 antibody.