CNT2 Polyclonal Antibody
- Catalog No.:YT1004
- Applications:WB;IHC;IF;ELISA
- Reactivity:Human;Mouse;Rat
- Target:
- CNT2
- Gene Name:
- SLC28A2
- Protein Name:
- Sodium/nucleoside cotransporter 2
- Human Gene Id:
- 9153
- Human Swiss Prot No:
- O43868
- Mouse Swiss Prot No:
- O88627
- Rat Gene Id:
- 60423
- Rat Swiss Prot No:
- Q62773
- Immunogen:
- The antiserum was produced against synthesized peptide derived from human SLC28A2. AA range:371-420
- Specificity:
- CNT2 Polyclonal Antibody detects endogenous levels of CNT2 protein.
- Formulation:
- Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
- Source:
- Polyclonal, Rabbit,IgG
- Dilution:
- WB 1:500 - 1:2000. IHC 1:100 - 1:300. ELISA: 1:10000.. IF 1:50-200
- Purification:
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
- Concentration:
- 1 mg/ml
- Storage Stability:
- -15°C to -25°C/1 year(Do not lower than -25°C)
- Other Name:
- SLC28A2;CNT2;Sodium/nucleoside cotransporter 2;Concentrative nucleoside transporter 2;CNT 2;hCNT2;Na(+)/nucleoside cotransporter 2;Sodium-coupled nucleoside transporter 2;Sodium/purine nucleoside co-transporter;SPNT;Solute carrier
- Observed Band(KD):
- 65kD
- Background:
- enzyme regulation:Inhibited by formycin B.,function:Sodium-dependent and purine-selective transporter. Exhibits the transport characteristics of the nucleoside transport system cif or N1 subtype (N1/cif) (selective for purine nucleosides and uridine). Plays a critical role in specific uptake and salvage of purine nucleosides in kidney and other tissues.,similarity:Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family.,tissue specificity:Expressed in heart and skeletal muscle followed by liver, kidney, intestine, pancreas, placenta and brain. Weak expression in lung.,
- Function:
- enzyme regulation:Inhibited by formycin B.,function:Sodium-dependent and purine-selective transporter. Exhibits the transport characteristics of the nucleoside transport system cif or N1 subtype (N1/cif) (selective for purine nucleosides and uridine). Plays a critical role in specific uptake and salvage of purine nucleosides in kidney and other tissues.,similarity:Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family.,tissue specificity:Expressed in heart and skeletal muscle followed by liver, kidney, intestine, pancreas, placenta and brain. Weak expression in lung.,
- Subcellular Location:
- Membrane ; Multi-pass membrane protein .
- Expression:
- Expressed in heart and skeletal muscle followed by liver, kidney, intestine, pancreas, placenta and brain (PubMed:9435697). Weak expression in lung (PubMed:9435697).
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- Antibody-FAQs
- Products Images
- Western Blot analysis of various cells using CNT2 Polyclonal Antibody
- Western Blot analysis of 3T3 cells using CNT2 Polyclonal Antibody
- Immunohistochemistry analysis of paraffin-embedded human lung carcinoma tissue, using SLC28A2 Antibody. The picture on the right is blocked with the synthesized peptide.
- Western blot analysis of lysates from Jurkat cells, using SLC28A2 Antibody. The lane on the right is blocked with the synthesized peptide.
- Western blot analysis of the lysates from HepG2 cells using SLC28A2 antibody.